Optimizing coverage for a Chlamydia trachomatis screening program

Yu Teng, Lanshan Han, Wanzhu Tu, Nan Kong

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

Chlamydia trachomatis infection, a major sexually transmitted disease, affects millions of people worldwide. A key public health challenge in managing such a transmitted disease is identifying infected but asymptomatic individuals so that they can be treated with antibiotics. Effectively resolving such a challenge will benefit both treated individuals (by improving quality of life) and the entire population (through reduced transmission). We adapt a well-established SEIRS (susceptible-exposed-infected-recovered-susceptible) model to evaluate the cost and effectiveness of different coverage levels of screening. To find the optimal screening rate, we formulate the question as a parameter optimization problem of ordinary differential equations and then apply a line search method which exhibits fast convergence. The numerical results as well as sensitivity analysis are presented in the paper.

Original languageEnglish (US)
Title of host publication2011 IEEE International Conference on Automation Science and Engineering, CASE 2011
Pages531-536
Number of pages6
DOIs
StatePublished - Dec 5 2011
Event2011 7th IEEE International Conference on Automation Science and Engineering, CASE 2011 - Trieste, Italy
Duration: Aug 24 2011Aug 27 2011

Publication series

NameIEEE International Conference on Automation Science and Engineering
ISSN (Print)2161-8070
ISSN (Electronic)2161-8089

Other

Other2011 7th IEEE International Conference on Automation Science and Engineering, CASE 2011
CountryItaly
CityTrieste
Period8/24/118/27/11

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ASJC Scopus subject areas

  • Control and Systems Engineering
  • Electrical and Electronic Engineering

Cite this

Teng, Y., Han, L., Tu, W., & Kong, N. (2011). Optimizing coverage for a Chlamydia trachomatis screening program. In 2011 IEEE International Conference on Automation Science and Engineering, CASE 2011 (pp. 531-536). [6042465] (IEEE International Conference on Automation Science and Engineering). https://doi.org/10.1109/CASE.2011.6042465