Oral antineoplastic handling at health care institutions in the United States: Survey of nurses and pharmacists

David J. Reeves, Teresa C. Kam, Susan H. Storey

Research output: Contribution to journalArticle

4 Scopus citations


Purpose: To characterize and identify trends in current practices for ordering, handling, dispensing, administering, and disposing of oral antineoplastics.Methods: An electronic survey was designed and sent to pharmacists and nurses via professional society listservs.Results: One hundred and twenty-three practitioners responded to the survey. Of those responding, 76% described having an official policy regarding the handling of oral antineoplastics. Prescribing was limited to attending physicians or oncologists the majority of the time (42% and 98%, respectively), with 11% accepting telephone orders for oral antineoplastics. Personal protective equipment was required by many of the respondents; 70% required gloves be worn. Patient contact precautions were utilized by 79% of practitioners, of which 81% followed similar precautions for targeted therapies. Compounding was required to be performed in a biological safety cabinet by 88% of respondents, and 83% required decontamination of supplies and equipment after exposure to oral antineoplastics.Conclusion: Although practices varied slightly, the majority of respondents follow available guidance when handling oral antineoplastics.

Original languageEnglish (US)
Pages (from-to)308-313
Number of pages6
JournalHospital Pharmacy
Issue number4
StatePublished - Apr 1 2013
Externally publishedYes


  • antineoplastic
  • chemotherapy
  • handling
  • hazardous
  • tyrosine kinase inhibitor

ASJC Scopus subject areas

  • Pharmacy
  • Pharmacology
  • Pharmacology (medical)

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