Oral lichen planus: clinical presentation and management.

Paul Edwards, Robert Kelsch

Research output: Contribution to journalArticle

108 Citations (Scopus)

Abstract

Oral lichen planus (OLP) is a chronic mucosal condition commonly encountered in clinical dental practice. Lichen planus is believed to represent an abnormal immune response in which epithelial cells are recognized as foreign, secondary to changes in the antigenicity of the cell surface. It has various oral manifestations, the reticular form being the most common. The erosive and atrophic forms of OLP are less common, yet are most likely to cause symptoms. Topical corticosteroids constitute the mainstay of treatment for symptomatic lesions of OLP. Recalcitrant lesions can be treated with systemic steroids or other systemic medications. However, there is only weak evidence that these treatments are superior to placebo. Given reports of a slightly greater risk of squamous cell carcinoma developing in areas of erosive OLP, it is important for clinicians to maintain a high index of suspicion for all intraoral lichenoid lesions. Periodic follow-up of all patients with OLP is recommended.

Original languageEnglish (US)
Pages (from-to)494-499
Number of pages6
JournalJournal (Canadian Dental Association)
Volume68
Issue number8
StatePublished - 2002
Externally publishedYes

Fingerprint

Oral Lichen Planus
Oral Manifestations
Lichen Planus
Squamous Cell Carcinoma
Tooth
Adrenal Cortex Hormones
Epithelial Cells
Steroids
Placebos
Therapeutics

Cite this

Oral lichen planus : clinical presentation and management. / Edwards, Paul; Kelsch, Robert.

In: Journal (Canadian Dental Association), Vol. 68, No. 8, 2002, p. 494-499.

Research output: Contribution to journalArticle

@article{654651bae99a4dbba89500931f4c1d83,
title = "Oral lichen planus: clinical presentation and management.",
abstract = "Oral lichen planus (OLP) is a chronic mucosal condition commonly encountered in clinical dental practice. Lichen planus is believed to represent an abnormal immune response in which epithelial cells are recognized as foreign, secondary to changes in the antigenicity of the cell surface. It has various oral manifestations, the reticular form being the most common. The erosive and atrophic forms of OLP are less common, yet are most likely to cause symptoms. Topical corticosteroids constitute the mainstay of treatment for symptomatic lesions of OLP. Recalcitrant lesions can be treated with systemic steroids or other systemic medications. However, there is only weak evidence that these treatments are superior to placebo. Given reports of a slightly greater risk of squamous cell carcinoma developing in areas of erosive OLP, it is important for clinicians to maintain a high index of suspicion for all intraoral lichenoid lesions. Periodic follow-up of all patients with OLP is recommended.",
author = "Paul Edwards and Robert Kelsch",
year = "2002",
language = "English (US)",
volume = "68",
pages = "494--499",
journal = "Journal (Canadian Dental Association)",
issn = "1488-2159",
publisher = "Canadian Dental Association",
number = "8",

}

TY - JOUR

T1 - Oral lichen planus

T2 - clinical presentation and management.

AU - Edwards, Paul

AU - Kelsch, Robert

PY - 2002

Y1 - 2002

N2 - Oral lichen planus (OLP) is a chronic mucosal condition commonly encountered in clinical dental practice. Lichen planus is believed to represent an abnormal immune response in which epithelial cells are recognized as foreign, secondary to changes in the antigenicity of the cell surface. It has various oral manifestations, the reticular form being the most common. The erosive and atrophic forms of OLP are less common, yet are most likely to cause symptoms. Topical corticosteroids constitute the mainstay of treatment for symptomatic lesions of OLP. Recalcitrant lesions can be treated with systemic steroids or other systemic medications. However, there is only weak evidence that these treatments are superior to placebo. Given reports of a slightly greater risk of squamous cell carcinoma developing in areas of erosive OLP, it is important for clinicians to maintain a high index of suspicion for all intraoral lichenoid lesions. Periodic follow-up of all patients with OLP is recommended.

AB - Oral lichen planus (OLP) is a chronic mucosal condition commonly encountered in clinical dental practice. Lichen planus is believed to represent an abnormal immune response in which epithelial cells are recognized as foreign, secondary to changes in the antigenicity of the cell surface. It has various oral manifestations, the reticular form being the most common. The erosive and atrophic forms of OLP are less common, yet are most likely to cause symptoms. Topical corticosteroids constitute the mainstay of treatment for symptomatic lesions of OLP. Recalcitrant lesions can be treated with systemic steroids or other systemic medications. However, there is only weak evidence that these treatments are superior to placebo. Given reports of a slightly greater risk of squamous cell carcinoma developing in areas of erosive OLP, it is important for clinicians to maintain a high index of suspicion for all intraoral lichenoid lesions. Periodic follow-up of all patients with OLP is recommended.

UR - http://www.scopus.com/inward/record.url?scp=0036731615&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036731615&partnerID=8YFLogxK

M3 - Article

C2 - 12323106

AN - SCOPUS:0036731615

VL - 68

SP - 494

EP - 499

JO - Journal (Canadian Dental Association)

JF - Journal (Canadian Dental Association)

SN - 1488-2159

IS - 8

ER -