Oral processing effort, appetite and acute energy intake in lean and obese adults

Richard D. Mattes, Robert Considine

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Chewing reportedly contributes to satiation and satiety signals. Attempts to document and quantify this have led to small and inconsistent effects. The present trial manipulated oral processing effort though required chewing of gums of different hardness and measured appetitive sensations, energy intake, gastric emptying, GI transit time, and concentrations of glucose, insulin, GLP-1, ghrelin and pancreatic polypeptide. Sixty adults classified by sex and BMI (15 each of lean females, obese females, lean males and obese males) were tested in a randomized, controlled, cross-over trial with three arms. They chewed nothing, soft gum or hard gum for 15. min while sipping grape juice (10% of individual energy needs) containing acetaminophen and lactulose on one day each separated by 7. days. Electromyographic recordings and self-reports were obtained during and after chewing to quantify oral processing effort. Blood was sampled through an indwelling catheter and appetite ratings were obtained at baseline and at 0, 15, 30, 45, 60, 90, 120, 180 and 240. min after chewing initiation. Breath samples were collected at 10. min intervals for the first 2. h and at 30. min intervals for the next 2. h. No effects of chewing were observed for appetitive sensations or gut peptide concentrations. Energy intake tended to decline in lean and increase in obese participants so that daily energy intake differed significantly between the two groups when chewing either gum, while no difference was observed on the non-chewing day. Serum glucose and insulin were significantly lower at selected time points 90-240. min after chewing compared to baseline and the non-chewing day. These data indicate chewing effort does not affect appetitive sensations or gut peptide secretion, but may exert a small differential effect on acute energy intake in lean and obese individuals and lead to greater post-prandial declines of serum glucose and insulin. The efficacy of gum chewing as a substitute for eating for weight management remains uncertain.

Original languageEnglish
Pages (from-to)173-181
Number of pages9
JournalPhysiology and Behavior
Volume120
DOIs
StatePublished - Aug 5 2013

Fingerprint

Mastication
Appetite
Energy Intake
Chewing Gum
Gingiva
Insulin
Glucose
Satiation
Lactulose
Pancreatic Polypeptide
Peptides
Ghrelin
Glucagon-Like Peptide 1
Indwelling Catheters
Gastric Emptying
Vitis
Hardness
Acetaminophen
Serum
Cross-Over Studies

Keywords

  • Appetite
  • Chew
  • Gum
  • Hunger
  • Obesity
  • Satiety

ASJC Scopus subject areas

  • Behavioral Neuroscience
  • Experimental and Cognitive Psychology
  • Philosophy

Cite this

Oral processing effort, appetite and acute energy intake in lean and obese adults. / Mattes, Richard D.; Considine, Robert.

In: Physiology and Behavior, Vol. 120, 05.08.2013, p. 173-181.

Research output: Contribution to journalArticle

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