Organ Toxicology

Michael Schwenk, Leslie Schwarz, John B. Watkins, Jürgen Pauluhn, Gunter P. Eckert, Walter E. Müller, Andreas Seeber, Tibor A. Rozman, Myriam Straube, Karl K. Rozman, Helmut Greim, Robert Snyder, Carol R. Gardner, Debra L. Laskin, Ines M. Lanzl

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Xenobiotic chemicals gain direct entry into the body via the gastrointestinal tract, which is the first organ that comes into contact with food-born foreign compounds. The major organs of the GI tract are the stomach, the small intestine, and the large intestine.

Original languageEnglish (US)
Title of host publicationToxicology and Risk Assessment
Subtitle of host publicationA Comprehensive Introduction
PublisherJohn Wiley & Sons, Ltd
Pages205-352
Number of pages148
ISBN (Print)9780470868935
DOIs
StatePublished - Feb 8 2008

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Keywords

  • Allergic contact dermato-conjunctivitis
  • Blood filtration and reabsorption
  • Gastric mucosa secretes enzymes
  • Immobilized antibody molecules
  • Interrelated neural systems
  • Mitochrondrial and microsomal cytochromes
  • Resident and recruited macrophages
  • Sensory-evoked potentials
  • Stratified squamous epithelium
  • Substance-related and adverse effects

ASJC Scopus subject areas

  • Chemistry(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Schwenk, M., Schwarz, L., Watkins, J. B., Pauluhn, J., Eckert, G. P., Müller, W. E., Seeber, A., Rozman, T. A., Straube, M., Rozman, K. K., Greim, H., Snyder, R., Gardner, C. R., Laskin, D. L., & Lanzl, I. M. (2008). Organ Toxicology. In Toxicology and Risk Assessment: A Comprehensive Introduction (pp. 205-352). John Wiley & Sons, Ltd. https://doi.org/10.1002/9780470868959.ch3