Orocecal transit during mild exercise in women

W. F. Keeling, Alon Harris, B. J. Martin

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Little is known of the influence of exercise on movement of ingested food through the alimentary tract or of the association of several gastrointestinal hormones with transit rate in exercise. In this study, orocecal transit during mild exercise was measured in 21 women by detecting a rise in expired H2 after ingestion of 20 g lactulose in a 350-ml (360 kcal) liquid meal. Motilin, gastrin, and cortisol were measured in peripheral venous blood when, as evidenced by a breath H2 rise, the first portion of the meal arrived at the cecum. Comparison was made between seated rest and a treadmill walk at 5.6 km/h up a 2% grade. The walk predictably elevated heart rate, O2 uptake, and rectal temperature and also reduced transit time from 98 min at rest to 75 min during exercise (P<0.001). Faster transit in exercise was associated with a significant rise in cortisol, while gastrin and motilin levels were both unchanged. In conclusion, in women mild concurrent exercise accelerates orocecal transit rate of at least the first portion of nonabsorbable carbohydrate in a liquid meal. Although the mechanism for the effect remains unknown, it may be secondary to some aspect of the stress response to physical activity.

Original languageEnglish
Pages (from-to)1350-1353
Number of pages4
JournalJournal of Applied Physiology
Volume68
Issue number4
StatePublished - 1990

Fingerprint

Exercise
Motilin
Meals
Gastrins
Hydrocortisone
Gastrointestinal Hormones
Lactulose
Cecum
Eating
Heart Rate
Carbohydrates
Food
Temperature

Keywords

  • cortisol
  • exercise motilin
  • gastrin
  • gastrointestinal motility
  • hydrogen
  • lactulose
  • oxygen uptake
  • progesterone
  • transit time

ASJC Scopus subject areas

  • Endocrinology
  • Physiology
  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

Cite this

Keeling, W. F., Harris, A., & Martin, B. J. (1990). Orocecal transit during mild exercise in women. Journal of Applied Physiology, 68(4), 1350-1353.

Orocecal transit during mild exercise in women. / Keeling, W. F.; Harris, Alon; Martin, B. J.

In: Journal of Applied Physiology, Vol. 68, No. 4, 1990, p. 1350-1353.

Research output: Contribution to journalArticle

Keeling, WF, Harris, A & Martin, BJ 1990, 'Orocecal transit during mild exercise in women', Journal of Applied Physiology, vol. 68, no. 4, pp. 1350-1353.
Keeling, W. F. ; Harris, Alon ; Martin, B. J. / Orocecal transit during mild exercise in women. In: Journal of Applied Physiology. 1990 ; Vol. 68, No. 4. pp. 1350-1353.
@article{fa24ace565c84bd2a113d8735014329e,
title = "Orocecal transit during mild exercise in women",
abstract = "Little is known of the influence of exercise on movement of ingested food through the alimentary tract or of the association of several gastrointestinal hormones with transit rate in exercise. In this study, orocecal transit during mild exercise was measured in 21 women by detecting a rise in expired H2 after ingestion of 20 g lactulose in a 350-ml (360 kcal) liquid meal. Motilin, gastrin, and cortisol were measured in peripheral venous blood when, as evidenced by a breath H2 rise, the first portion of the meal arrived at the cecum. Comparison was made between seated rest and a treadmill walk at 5.6 km/h up a 2{\%} grade. The walk predictably elevated heart rate, O2 uptake, and rectal temperature and also reduced transit time from 98 min at rest to 75 min during exercise (P<0.001). Faster transit in exercise was associated with a significant rise in cortisol, while gastrin and motilin levels were both unchanged. In conclusion, in women mild concurrent exercise accelerates orocecal transit rate of at least the first portion of nonabsorbable carbohydrate in a liquid meal. Although the mechanism for the effect remains unknown, it may be secondary to some aspect of the stress response to physical activity.",
keywords = "cortisol, exercise motilin, gastrin, gastrointestinal motility, hydrogen, lactulose, oxygen uptake, progesterone, transit time",
author = "Keeling, {W. F.} and Alon Harris and Martin, {B. J.}",
year = "1990",
language = "English",
volume = "68",
pages = "1350--1353",
journal = "Journal of Applied Physiology",
issn = "8750-7587",
publisher = "American Physiological Society",
number = "4",

}

TY - JOUR

T1 - Orocecal transit during mild exercise in women

AU - Keeling, W. F.

AU - Harris, Alon

AU - Martin, B. J.

PY - 1990

Y1 - 1990

N2 - Little is known of the influence of exercise on movement of ingested food through the alimentary tract or of the association of several gastrointestinal hormones with transit rate in exercise. In this study, orocecal transit during mild exercise was measured in 21 women by detecting a rise in expired H2 after ingestion of 20 g lactulose in a 350-ml (360 kcal) liquid meal. Motilin, gastrin, and cortisol were measured in peripheral venous blood when, as evidenced by a breath H2 rise, the first portion of the meal arrived at the cecum. Comparison was made between seated rest and a treadmill walk at 5.6 km/h up a 2% grade. The walk predictably elevated heart rate, O2 uptake, and rectal temperature and also reduced transit time from 98 min at rest to 75 min during exercise (P<0.001). Faster transit in exercise was associated with a significant rise in cortisol, while gastrin and motilin levels were both unchanged. In conclusion, in women mild concurrent exercise accelerates orocecal transit rate of at least the first portion of nonabsorbable carbohydrate in a liquid meal. Although the mechanism for the effect remains unknown, it may be secondary to some aspect of the stress response to physical activity.

AB - Little is known of the influence of exercise on movement of ingested food through the alimentary tract or of the association of several gastrointestinal hormones with transit rate in exercise. In this study, orocecal transit during mild exercise was measured in 21 women by detecting a rise in expired H2 after ingestion of 20 g lactulose in a 350-ml (360 kcal) liquid meal. Motilin, gastrin, and cortisol were measured in peripheral venous blood when, as evidenced by a breath H2 rise, the first portion of the meal arrived at the cecum. Comparison was made between seated rest and a treadmill walk at 5.6 km/h up a 2% grade. The walk predictably elevated heart rate, O2 uptake, and rectal temperature and also reduced transit time from 98 min at rest to 75 min during exercise (P<0.001). Faster transit in exercise was associated with a significant rise in cortisol, while gastrin and motilin levels were both unchanged. In conclusion, in women mild concurrent exercise accelerates orocecal transit rate of at least the first portion of nonabsorbable carbohydrate in a liquid meal. Although the mechanism for the effect remains unknown, it may be secondary to some aspect of the stress response to physical activity.

KW - cortisol

KW - exercise motilin

KW - gastrin

KW - gastrointestinal motility

KW - hydrogen

KW - lactulose

KW - oxygen uptake

KW - progesterone

KW - transit time

UR - http://www.scopus.com/inward/record.url?scp=0025271808&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025271808&partnerID=8YFLogxK

M3 - Article

VL - 68

SP - 1350

EP - 1353

JO - Journal of Applied Physiology

JF - Journal of Applied Physiology

SN - 8750-7587

IS - 4

ER -