Osteoclasts Pump Iron

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Osteoclasts are the primary cells that resorb bone; they require high energy levels to degrade bone matrix, releasing minerals to maintain calcium homeostasis. Recent work on osteoclast differentiation and activity highlights an important role for mitochondrial biogenesis and explores the role of iron transferrin in generating a positive osteoclastogenic feedback loop.

Original languageEnglish (US)
Pages (from-to)405-406
Number of pages2
JournalCell Metabolism
Volume9
Issue number5
DOIs
StatePublished - May 6 2009
Externally publishedYes

Fingerprint

Osteoclasts
Iron
Bone Matrix
Organelle Biogenesis
Transferrin
Minerals
Homeostasis
Calcium
Bone and Bones

ASJC Scopus subject areas

  • Cell Biology
  • Molecular Biology
  • Physiology

Cite this

Osteoclasts Pump Iron. / Roodman, G. David.

In: Cell Metabolism, Vol. 9, No. 5, 06.05.2009, p. 405-406.

Research output: Contribution to journalArticle

Roodman, G. David. / Osteoclasts Pump Iron. In: Cell Metabolism. 2009 ; Vol. 9, No. 5. pp. 405-406.
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