Osteocyte Messages from a Bony Tomb

Research output: Contribution to journalShort survey

32 Scopus citations


Until recently, osteocytes have escaped the limelight, embedded within their cave-like lacunae in the mineralized matrix of bone. In this issue of Cell Metabolism, Tatsumi et al. (2007) present evidence that this "third bone cell" can send either inhibitory signals to osteoclasts to maintain bone mass with normal loading or stimulatory signals to osteoclasts to initiate bone loss upon immobilization, thereby playing an indispensable role in skeletal homeostasis.

Original languageEnglish (US)
Pages (from-to)410-411
Number of pages2
JournalCell Metabolism
Issue number6
StatePublished - Jun 6 2007
Externally publishedYes


ASJC Scopus subject areas

  • Physiology
  • Molecular Biology
  • Cell Biology

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