Osteocyte Messages from a Bony Tomb

Research output: Contribution to journalShort survey

31 Citations (Scopus)

Abstract

Until recently, osteocytes have escaped the limelight, embedded within their cave-like lacunae in the mineralized matrix of bone. In this issue of Cell Metabolism, Tatsumi et al. (2007) present evidence that this "third bone cell" can send either inhibitory signals to osteoclasts to maintain bone mass with normal loading or stimulatory signals to osteoclasts to initiate bone loss upon immobilization, thereby playing an indispensable role in skeletal homeostasis.

Original languageEnglish (US)
Pages (from-to)410-411
Number of pages2
JournalCell Metabolism
Volume5
Issue number6
DOIs
StatePublished - Jun 6 2007
Externally publishedYes

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Osteocytes
Osteoclasts
Bone and Bones
Bone Matrix
Immobilization
Homeostasis

ASJC Scopus subject areas

  • Cell Biology
  • Molecular Biology
  • Physiology

Cite this

Osteocyte Messages from a Bony Tomb. / Bonewald, Lynda.

In: Cell Metabolism, Vol. 5, No. 6, 06.06.2007, p. 410-411.

Research output: Contribution to journalShort survey

Bonewald, Lynda. / Osteocyte Messages from a Bony Tomb. In: Cell Metabolism. 2007 ; Vol. 5, No. 6. pp. 410-411.
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