Osteocytes

Research output: Chapter in Book/Report/Conference proceedingChapter

7 Citations (Scopus)

Abstract

Osteocytes are thought to function as a network of sensory cells mediating the effects of mechanical loading through this extensive lacunocanalicular network. The chapter focuses on the ontogeny, apoptosis and modification of the microenvironment of osteocytes. It describes the mechanosensation and transduction mechanisms. Further, it discusses the role of gap junctions and hemichannels in osteocyte communication. Finally, the chapter talks about the potential role of osteocytes in bone disease. It is most likely that osteocytes utilize undiscovered specific molecules to regulate bone remodeling.

Original languageEnglish (US)
Title of host publicationPrimer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism: Eighth Edition
PublisherWiley Blackwell
Pages34-41
Number of pages8
ISBN (Electronic)9781118453926
ISBN (Print)9781118453889
DOIs
StatePublished - Jul 19 2013
Externally publishedYes

Fingerprint

Osteocytes
Bone
Apoptosis
Molecules
Communication
Bone Remodeling
Gap Junctions
Bone Diseases

Keywords

  • Apoptosis
  • Bone remodeling
  • Gap junctions
  • Hemichannels
  • Mechanosensation
  • Ontogeny
  • Osteocytes
  • Transduction

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Bonewald, L. (2013). Osteocytes. In Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism: Eighth Edition (pp. 34-41). Wiley Blackwell. https://doi.org/10.1002/9781118453926.ch4

Osteocytes. / Bonewald, Lynda.

Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism: Eighth Edition. Wiley Blackwell, 2013. p. 34-41.

Research output: Chapter in Book/Report/Conference proceedingChapter

Bonewald, L 2013, Osteocytes. in Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism: Eighth Edition. Wiley Blackwell, pp. 34-41. https://doi.org/10.1002/9781118453926.ch4
Bonewald L. Osteocytes. In Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism: Eighth Edition. Wiley Blackwell. 2013. p. 34-41 https://doi.org/10.1002/9781118453926.ch4
Bonewald, Lynda. / Osteocytes. Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism: Eighth Edition. Wiley Blackwell, 2013. pp. 34-41
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