Osteocytes as multifunctional cells

Research output: Contribution to journalArticlepeer-review

38 Scopus citations

Abstract

In summary, the proposed functions of osteocytes include the translation of mechanical strain into signals of bone formation or of bone resorption, as modifiers of their microenvironment thereby modifying the properties of bone and the magnitude of shear stress in the bone fluid, as regulators of mineralization and as regulators of phosphate homeostasis. These cells may act as more than orchestrators of resorption or formation in response to strain. This information and the fact that these cells can move within their lacunae should dispel any notion that these cells are inactive, place holders.

Original languageEnglish (US)
Pages (from-to)331-333
Number of pages3
JournalJournal of Musculoskeletal Neuronal Interactions
Volume6
Issue number4
StatePublished - Oct 1 2006
Externally publishedYes

Keywords

  • Mechanical load
  • Mineral metabolism
  • Osteocytes

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Physiology
  • Orthopedics and Sports Medicine

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