Outcomes analysis of mandibular distraction osteogenesis for the treatment of pierre robin sequence

Kariuki P. Murage, Sunil S. Tholpady, Michael Friel, Robert J. Havlik, Roberto L. Flores

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

Mandibular distraction osteogenesis is an established technique used to treat infants with Pierre Robin sequence associated with severe airway obstruction. The authors present a 7-year retrospective review of all patients with Pierre Robin sequence treated with mandibular distraction osteogenesis. Recorded variables included improvements in apnea/hypopnea index and postintervention tracheostomy. Multiple preoperative variables were assessed for association with successful mandibular distraction osteogenesis or tracheostomy. Fifty patients were identified for this study. Four patients (8 percent) required tracheostomy after distraction. A Fisher's exact test demonstrated no statistical association of tracheostomy with prematurity, low birth weight, preoperative intubation, late intervention, genetic syndromes, cardiac abnormalities, pulmonary abnormalities, or gastrostomy tube. The absence of a cleft palate, gastroesophageal reflux disease, and need for Nissen fundoplication were associated with failure of distraction. Clinical Question/Level of Evidence: Therapeutic, IV.

Original languageEnglish
Pages (from-to)419-421
Number of pages3
JournalPlastic and Reconstructive Surgery
Volume132
Issue number2
DOIs
StatePublished - Aug 2013

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Pierre Robin Syndrome
Distraction Osteogenesis
Tracheostomy
Fundoplication
Gastrostomy
Genetic Engineering
Cleft Palate
Low Birth Weight Infant
Apnea
Airway Obstruction
Therapeutics
Gastroesophageal Reflux
Intubation
Lung

ASJC Scopus subject areas

  • Surgery

Cite this

Outcomes analysis of mandibular distraction osteogenesis for the treatment of pierre robin sequence. / Murage, Kariuki P.; Tholpady, Sunil S.; Friel, Michael; Havlik, Robert J.; Flores, Roberto L.

In: Plastic and Reconstructive Surgery, Vol. 132, No. 2, 08.2013, p. 419-421.

Research output: Contribution to journalArticle

Murage, Kariuki P. ; Tholpady, Sunil S. ; Friel, Michael ; Havlik, Robert J. ; Flores, Roberto L. / Outcomes analysis of mandibular distraction osteogenesis for the treatment of pierre robin sequence. In: Plastic and Reconstructive Surgery. 2013 ; Vol. 132, No. 2. pp. 419-421.
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