p75 Neurotrophin receptor immunoreactivity in the aged human hypothalamus

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Low-affinity p75 neurotrophin receptor (p75(NTR)) immunoreactivity in the aged human hypothalamus was examined in autopsied material. Numerous p75(NTR)-immunoreactive cells were found in the paraventricular and supraoptic hypothalamic nuclei. The suprachiasmatic nucleus was devoid of p75(NTR)-immunostaining. Many p75(NTR)-immunoreactive fibers extended laterally and ventrally from the paraventricular and supraoptic nuclei into the pituitary stalk and median eminence. Our results suggest that neurotrophins may be present within the human hypothalamo-hypophyseal system.

Original languageEnglish
Pages (from-to)9-12
Number of pages4
JournalNeuroscience Letters
Volume231
Issue number1
DOIs
StatePublished - Aug 1 1997

Fingerprint

Nerve Growth Factor Receptor
Hypothalamus
Supraoptic Nucleus
Paraventricular Hypothalamic Nucleus
Hypothalamo-Hypophyseal System
Median Eminence
Suprachiasmatic Nucleus
Nerve Growth Factors
Pituitary Gland

Keywords

  • Nerve growth factor
  • Paraventricular hypothalamic nucleus
  • Suprachiasmatic nucleus
  • Supraoptic nucleus

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

p75 Neurotrophin receptor immunoreactivity in the aged human hypothalamus. / Moga, Margaret; Duong, Taihung.

In: Neuroscience Letters, Vol. 231, No. 1, 01.08.1997, p. 9-12.

Research output: Contribution to journalArticle

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AB - Low-affinity p75 neurotrophin receptor (p75(NTR)) immunoreactivity in the aged human hypothalamus was examined in autopsied material. Numerous p75(NTR)-immunoreactive cells were found in the paraventricular and supraoptic hypothalamic nuclei. The suprachiasmatic nucleus was devoid of p75(NTR)-immunostaining. Many p75(NTR)-immunoreactive fibers extended laterally and ventrally from the paraventricular and supraoptic nuclei into the pituitary stalk and median eminence. Our results suggest that neurotrophins may be present within the human hypothalamo-hypophyseal system.

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