Pancreatic islet-acinar cell interaction: Amylase messenger RNA levels are determined by insulin

Murray Korc, David Owerbach, Carmen Quinto, William J. Rutter

Research output: Contribution to journalArticle

219 Scopus citations

Abstract

Pancreatic amylase messenger RNA progressively decreases in rats rendered diabetic with streptozotocin. Insulin reverses this effect, inducing a selective increase in amylase messenger RNA in the pancreas. Parotid amylase messenger RNA is not significantly affected by either diabetes or insulin.

Original languageEnglish (US)
Pages (from-to)351-353
Number of pages3
JournalScience
Volume213
Issue number4505
DOIs
StatePublished - Jan 1 1981

ASJC Scopus subject areas

  • General

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