Panoramic epifluorescent visualization of cardiac action potential activity

Mark Anthony Bray, Shien Fong Lin, John P. Wikswo

Research output: Contribution to journalConference article

2 Scopus citations

Abstract

Optical imaging of transmembrane potentials in cardiac tissue is a rapidly growing technique in cardiac electrophysiology. Current studies typically use a monocular imaging setup, thus limiting investigation to a restricted region of tissue. However, studies of large-scale wavefront dynamics, especially those during fibrillation and defibrillation, require visualization of the entire epicardial surface. We have developed a panoramic cardiac visualization system using mirrors which performs two tasks: 1) reconstruction of the surface geometry of the heart, and 2) representation of the panoramic fluorescence information as a texture mapping onto the geometry that was previously created. This system permits measurement of epicardial electrodynamics over a geometrically realistic representation of the actual heart being studied.

Original languageEnglish (US)
Pages (from-to)99-107
Number of pages9
JournalProceedings of SPIE - The International Society for Optical Engineering
Volume3658
StatePublished - Jan 1 1999
Externally publishedYes
EventProceedings of the 1999 Medical Imaging - Image Dispaly - San Diego, CA, USA
Duration: Feb 21 1999Feb 23 1999

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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