Papillary serous carcinoma of the retroperitoneum

Thomas Ulbright, D. J. Morley, L. M. Roth, R. L. Berkow

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

We describe a retroperitoneal neoplasm in an 11-year-old girl which had a light microscopic appearance identical to that of papillary serous carcinoma of the ovary. There was no evidence of ovarian involvement. Immunohistochemical staining for amylase was positive within the cytoplasm of tumor cells. Since amylase is a marker for serous ovarian tumors, this finding supports the belief that 'ovarian-type' neoplasms that occur at ectopic locations are essentially identical to their ovarian counterparts. We believe they originate from metaplasia of mesothelium. Our findings support the concept that these tumors should exhibit a biological behavior and therapeutic response which are similar to those of an ovarian tumor of the same grade and comparable stage. The demonstration of intracytoplasmic amylase also may prove useful in differentiating peritoneal serous tumors from non-metaplastic mesothelial proliferations. We are unaware of a prior report of an extraovarian serous carcinoma in a child.

Original languageEnglish
Pages (from-to)633-637
Number of pages5
JournalAmerican Journal of Clinical Pathology
Volume79
Issue number5
StatePublished - 1983

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Papillary Carcinoma
Amylases
Neoplasms
Retroperitoneal Neoplasms
Metaplasia
Ovarian Neoplasms
Ovary
Cytoplasm
Epithelium
Staining and Labeling
Carcinoma
Light

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Ulbright, T., Morley, D. J., Roth, L. M., & Berkow, R. L. (1983). Papillary serous carcinoma of the retroperitoneum. American Journal of Clinical Pathology, 79(5), 633-637.

Papillary serous carcinoma of the retroperitoneum. / Ulbright, Thomas; Morley, D. J.; Roth, L. M.; Berkow, R. L.

In: American Journal of Clinical Pathology, Vol. 79, No. 5, 1983, p. 633-637.

Research output: Contribution to journalArticle

Ulbright, T, Morley, DJ, Roth, LM & Berkow, RL 1983, 'Papillary serous carcinoma of the retroperitoneum', American Journal of Clinical Pathology, vol. 79, no. 5, pp. 633-637.
Ulbright, Thomas ; Morley, D. J. ; Roth, L. M. ; Berkow, R. L. / Papillary serous carcinoma of the retroperitoneum. In: American Journal of Clinical Pathology. 1983 ; Vol. 79, No. 5. pp. 633-637.
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