A high proportion of extremely low birth weight (ELBW) infants experience poor growth in the neonatal intensive care unit. Nutritional deficits that rapidly accumulate shortly after birth are a major factor in these growth outcomes.Nutritional deficits can be minimized and growth outcomes improved by beginning parenteral nutrition soon after birth. Initial support should include glucose at 4-7 mg/kg per min, amino acids at 2-3 g/kg per day, and lipids at 2 g/kg per day.Goals for full parenteral nutrition support in ELBW infants are 90-100 kcal/kg per day (13-15 g/kg per day glucose, 3-4 g/kg per day lipid, 3.5-4.0 g/kg per day amino acids).There is increasing attention to fish oil-based lipid solutions, which appear to ameliorate parenteral nutrition-associated liver disease in infants that require long-term intravenous nutrition. These products are currently not commercially available in the United States. Randomized trials evaluating fish oil-based and other new parenteral nutrition solutions in preterm infants are greatly needed.
|Original language||English (US)|
|Title of host publication||Avery's Diseases of the Newborn|
|Subtitle of host publication||Tenth Edition|
|State||Published - Jan 1 2018|
- Parenteral nutrition
ASJC Scopus subject areas