Parietal lobe epilepsy

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Patients with parietal lobe epilepsy (PLE) exhibit an electroclinical epilepsy syndrome that is rarely seen even at large epilepsy centers. Clinically, most patients with PLE exhibit a somatosensory aura that may include painful dysesthesias, though vertigo, aphasia, disturbances of one's body image also occur, when ictal propagation occurs from the parietal lobe to the supplementary motor area, hypermotor manifestations are noted. When temporolimbic propagation occurs, complex visual or auditory hallucinations and automatisms may appear. Scalp electroencephalogram (EEG) is often nonlocalizing. Ictal EEG is rarely localizing in PLE, and invasive EEG is often required for definitive localization and functional mapping. Recent advances in clinical neurophysiology during the evaluation of patients with refractory partial epilepsy include Ictal magnetic source imaging (MSI). Combined EEG and functional magnetic resonance imaging (EEG-fMRI) may be useful for patients with PLE to refine the localization in patients undergoing a presurgical evaluation. High-frequency oscillations (HFOs) are more concentrated inside the seizure onset zone (SOZ), indicating that they may be used as interictal scalp EEG biomarker for the SOZ. When medical therapy fails, resective epilepsy surgery can result in seizure freedom or significant reduction especially when a lesion is present.

Original languageEnglish
Pages (from-to)392-396
Number of pages5
JournalJournal of Clinical Neurophysiology
Volume29
Issue number5
DOIs
StatePublished - Oct 2012

Fingerprint

Parietal Lobe
Epilepsy
Electroencephalography
Seizures
Hallucinations
Stroke
Scalp
Automatism
Neurophysiology
Partial Epilepsy
Paresthesia
Body Image
Aphasia
Vertigo
Motor Cortex
Biomarkers
Magnetic Resonance Imaging

Keywords

  • Epilepsy
  • fMRI
  • HFO
  • MEG
  • Parietal
  • Surgery

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Physiology
  • Physiology (medical)

Cite this

Parietal lobe epilepsy. / Salanova, Vicenta.

In: Journal of Clinical Neurophysiology, Vol. 29, No. 5, 10.2012, p. 392-396.

Research output: Contribution to journalArticle

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