Pathogenesis of acute kidney injury

David Basile, Rajasree Sreedharan, Scott K. van Why

Research output: Chapter in Book/Report/Conference proceedingChapter


The sudden loss of renal function that may result from inadequate renal perfusion, arterial or venous obstruction, renal cell injury, or acute obstruction to urine flow historically has been termed acute renal failure (ARF). Several years ago the term acute kidney injury (AKI) was proposed to replace the term ARF [1]. Usage of “AKI” is now widespread. Unfortunately it is often used imprecisely, defeating the purpose of the change in nomenclature.

Original languageEnglish (US)
Title of host publicationPediatric Nephrology, Seventh Edition
PublisherSpringer Berlin Heidelberg
Number of pages38
ISBN (Print)9783662435960, 9783662435953
StatePublished - Jan 1 2015

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Basile, D., Sreedharan, R., & van Why, S. K. (2015). Pathogenesis of acute kidney injury. In Pediatric Nephrology, Seventh Edition (pp. 2101-2138). Springer Berlin Heidelberg.