Pathologic handling and reporting of prostate tissue specimens in patients receiving neoadjuvant hormonal therapy: Report of the pathology committee

D. J. Grignon, D. G. Bostwick, F. Civantos, M. B. Garnick, P. Gaudin, J. R. Srigley, C. Sternberg, S. Howell, P. Albertsen, W. Fair

Research output: Contribution to journalArticle

17 Scopus citations

Abstract

Prior meetings of the International Conference on Neoadjuvant Hormonal Therapy in Prostate Cancer identified areas of concern in the pathologic analysis of post-treatment specimens. In response, a pathology subcommittee was formed to address the questions that had been raised. Recommendations are made here concerning pretreatment biopsy review and reporting, handling and reporting of radical prostatectomy specimens, Gleason scoring of treated cancer, grading of therapy effect, role of immunohistochemistry procedures, and the significance of high-grade prostatic intraepithelial neoplasia. Neoadjuvant trials with both surgery and radiation therapy were considered in drawing up these recommendations.

Original languageEnglish (US)
Pages (from-to)193-200
Number of pages8
JournalMolecular Urology
Volume3
Issue number3
StatePublished - Jan 1 1999

ASJC Scopus subject areas

  • Urology

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    Grignon, D. J., Bostwick, D. G., Civantos, F., Garnick, M. B., Gaudin, P., Srigley, J. R., Sternberg, C., Howell, S., Albertsen, P., & Fair, W. (1999). Pathologic handling and reporting of prostate tissue specimens in patients receiving neoadjuvant hormonal therapy: Report of the pathology committee. Molecular Urology, 3(3), 193-200.