Pathology of the hard tissues of the jaws

Research output: Chapter in Book/Report/Conference proceedingChapter


This chapter provides a brief review of some of the more common of pathological entities: tooth demineralization, dental caries, root resorption, odontogenic cysts, odontogenic neoplasms, and nonodontogenic tumors of the jaw. A substantial number of additional nonodontogenic cysts, pseudocysts, and tumors can also occur in the jaws. Among these is a process unique to the jaws: the central giant cell lesion (CGCL). Odontogenic cysts and neoplasms originate in the tooth-bearing areas of the jaws, and are characterized by replacement of bone by soft tissue or, less commonly, a mixture of soft and hard tissue. In the absence of secondary infection or significant expansion, odontogenic cysts and tumors typically cause few symptoms and are usually identified during routine dental radiographic examination. Regardless of the treatment approach selected, patients with a history of odontogenic keratocyst (OKC) should be followed radiographically for an indefinite period, as recurrences have been documented even decades after treatment.

Original languageEnglish (US)
Title of host publicationPrimer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism
Number of pages9
ISBN (Electronic)9781119266594
ISBN (Print)9781119266563
StatePublished - Jan 1 2018
Externally publishedYes


  • Central giant cell lesion
  • Dental caries
  • Hard tissue organs
  • Jaw malignancies
  • Nonodontogenic tumors
  • Odontogenic cysts
  • Odontogenic neoplasm
  • Pathological entities
  • Root resorption
  • Tooth demineralization

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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  • Cite this

    Edwards, P. (2018). Pathology of the hard tissues of the jaws. In Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism (pp. 918-926). wiley.