Peak bone mass in young women

Dorothy Teegarden, William R. Proulx, Berdine R. Martin, Jian Zhao, George P. Mccabe, Roseann M. Lyle, Munro Peacock, Charles Slemenda, C. Conrad Johnston, Connie M. Weaver

Research output: Contribution to journalArticle

237 Citations (Scopus)

Abstract

Increasing peak bone mineral density (BMD) or content (BMC) in young women may help to reduce the incidence of osteoporosis. Identifying the age when peak bone content or density is attained is essential to develop strategies aimed at optimizing peak BMD and BMC. Total body bone mineral density (TBBMD) and content (TBBMC) were measured by a dual X-ray absorptiometer in healthy females (n = 247, aged 11-32 years). TBBMD and TBBMC were modeled separately as a nonlinear function of age. By age 22.1 ± 2.5 years, 99% of peak BMD is attained, and by age 26.2 ± 3.7 years, 99% of peak BMC is attained. Nonlinear relationships between weight and TBBMD or TBBMC were also modeled. In this model, the influence of several parameters, including age, weight, and height, on BMC and BMD were simultaneously assessed. A model with age and weight described the best fit for TBBMD, whereas age, weight, and height described the best fit for total body TBBMC.

Original languageEnglish
Pages (from-to)711-715
Number of pages5
JournalJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Volume10
Issue number5
StatePublished - May 1995

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Bone Density
Bone and Bones
Weights and Measures
Osteoporosis
Body Weight
X-Rays

ASJC Scopus subject areas

  • Surgery

Cite this

Teegarden, D., Proulx, W. R., Martin, B. R., Zhao, J., Mccabe, G. P., Lyle, R. M., ... Weaver, C. M. (1995). Peak bone mass in young women. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 10(5), 711-715.

Peak bone mass in young women. / Teegarden, Dorothy; Proulx, William R.; Martin, Berdine R.; Zhao, Jian; Mccabe, George P.; Lyle, Roseann M.; Peacock, Munro; Slemenda, Charles; Johnston, C. Conrad; Weaver, Connie M.

In: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 10, No. 5, 05.1995, p. 711-715.

Research output: Contribution to journalArticle

Teegarden, D, Proulx, WR, Martin, BR, Zhao, J, Mccabe, GP, Lyle, RM, Peacock, M, Slemenda, C, Johnston, CC & Weaver, CM 1995, 'Peak bone mass in young women', Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, vol. 10, no. 5, pp. 711-715.
Teegarden D, Proulx WR, Martin BR, Zhao J, Mccabe GP, Lyle RM et al. Peak bone mass in young women. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 1995 May;10(5):711-715.
Teegarden, Dorothy ; Proulx, William R. ; Martin, Berdine R. ; Zhao, Jian ; Mccabe, George P. ; Lyle, Roseann M. ; Peacock, Munro ; Slemenda, Charles ; Johnston, C. Conrad ; Weaver, Connie M. / Peak bone mass in young women. In: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 1995 ; Vol. 10, No. 5. pp. 711-715.
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