Pediatric extranodal marginal zone B-cell lymphoma presenting as amyloidosis in minor salivary glands: A case report and review of the literature

Ali Gabali, Charles W. Ross, Paul Edwards, Bertram Schnitzer, Theodora E. Danciu

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

We report an unusual case of an extranodal marginal zone B-cell lymphoma (EMZL) arising in the labial minor salivary gland in an immunocompetent 11-year-old boy. The initial histopathologic review favored localized amyloidosis. However, further evaluation supported the diagnosis of low-grade B-cell lymphoma with plasmacytic differentiation, surrounded by deposits of AL κ-type amyloid. Clinical management consisted of excision with no recurrence at 1-year follow-up. This case demonstrates that a diagnosis of lymphoma must be considered in cases of amyloidosis associated with minor salivary gland involvement, even in children. In addition, we provide a literature review of extranodal marginal zone B-cell lymphoma arising in salivary glands.

Original languageEnglish (US)
JournalJournal of Pediatric Hematology/Oncology
Volume35
Issue number3
DOIs
StatePublished - Apr 2013
Externally publishedYes

Fingerprint

Minor Salivary Glands
Marginal Zone B-Cell Lymphoma
Amyloidosis
Pediatrics
Amyloid Plaques
B-Cell Lymphoma
Lip
Salivary Glands
Non-Hodgkin's Lymphoma
Lymphoma
Recurrence

Keywords

  • Amyloidosis
  • Immunocompetent child
  • Lymphoma
  • Salivary glands

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Oncology
  • Hematology

Cite this

Pediatric extranodal marginal zone B-cell lymphoma presenting as amyloidosis in minor salivary glands : A case report and review of the literature. / Gabali, Ali; Ross, Charles W.; Edwards, Paul; Schnitzer, Bertram; Danciu, Theodora E.

In: Journal of Pediatric Hematology/Oncology, Vol. 35, No. 3, 04.2013.

Research output: Contribution to journalArticle

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