Pediatric germ cell tumors

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Pediatric germ cell tumors represent a diverse group of tumors that present from in utero through adolescence at many nongonadal locations, from the neck to the sacrococcygeal region. Surgical resection remains the central element of management, and accurate surgical staging is essential to properly ascertain the correct risk-based treatment. The management for all benign tumors (mature and immature teratomas) and select completely resectable malignant tumors is surgery alone. Modern-day chemotherapy is extremely effective in infants and children with unresectable and metastatic disease and these children have a very high survival rate. The use of neoadjuvant chemotherapy allows vital organ preservation and there is no role for resection of vital structures at the time of initial presentation.

Original languageEnglish
Pages (from-to)51-60
Number of pages10
JournalSeminars in Pediatric Surgery
Volume21
Issue number1
DOIs
StatePublished - Feb 2012

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Germ Cell and Embryonal Neoplasms
Teratoma
Pediatrics
Sacrococcygeal Region
Organ Preservation
Drug Therapy
Neoplasms
Neck
Therapeutics

Keywords

  • Extragonadal tumors
  • Germ cell tumor
  • Ovary
  • Testes

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Surgery

Cite this

Pediatric germ cell tumors. / Rescorla, Frederick.

In: Seminars in Pediatric Surgery, Vol. 21, No. 1, 02.2012, p. 51-60.

Research output: Contribution to journalArticle

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