Perceived Stress and the Fatigue Symptom Cluster in Childhood Brain Tumor Survivors

Ann Johnson, Marti Rice, Anne Turner-Henson, Joan Haase, Andres Azuero

Research output: Contribution to journalArticle

2 Scopus citations


SAMPLE & SETTING: Child participants completed treatment at least six months and less than six years prior to enrollment at Children's Hospital of Alabama in Birmingham or Cook Children's Medical Center in Fort Worth, Texas.

METHODS & VARIABLES: With cross-sectional methods, the authors measured child-perceived stress, sleep-wake disturbance (SWD) (parent report), and fatigue. Children also provided saliva samples for cortisol measurement (stress response) and completed actigraphy sleep monitoring.

RESULTS: Mild to moderate stress, SWD, and fatigue were reported, and a wide range of sleep times and cortisol levels were noted. Meaningful effect sizes in relationships between variables were found.

IMPLICATIONS FOR NURSING: The stress, SWD, and fatigue symptom cluster in survivorship necessitates routine nursing assessment.

OBJECTIVES: To explore and estimate relationships among the elements of the symptom cluster in survivors of brain tumors aged 8-12 years during early survivorship.

Original languageEnglish (US)
Pages (from-to)775-785
Number of pages11
JournalOncology Nursing Forum
Issue number6
StatePublished - Nov 1 2018


  • brain tumor
  • cancer
  • childhood
  • fatigue
  • sleep
  • stress
  • survivorship
  • symptom cluster

ASJC Scopus subject areas

  • Oncology(nursing)

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