Percutaneous pulsed-dye laser lithotripsy of gallbladder stones in swine

Terry K. Kopecky, Robert H. Hawes, Michael L. Bogan, Steven L. Griffith, R. Gerald Dreesen, Thomas M. Ulbright

Research output: Contribution to journalArticle

6 Scopus citations


Human gallstones were surgically implanted in the gallbladders of 14 pigs. Nine to 16 days later a sheath was successfully placed percutaneously into the gallbladders of 13 animals using ultrasound and fluoroscopy. Two methods were used to guide laser fragmentation: (1) fluoroscopy and a steerable double lumen catheter (two animals), and (2) a flexible endoscope (11 animals). Laser treatment was done in 12 animals with a flashlamp-pumped pulsed-dye laser. A mean of 3600 pulses/animal were delivered using a wavelength of 504 nm and a maximum energy of 60 m/pulse. No fragmentation occurred in two animals, partial fragmentation occurred in six, and complete fragmentation occurred in four. Endoscopic guidance was superior to fluoroscopic guidance. Complications (sheath dislodgment, gallbladder perforation, bleeding) occurred in eight of 14 animals. Pulsed-dye laser fragmentation of gallbladder stones is feasible using endoscopic guidance. The use of this technique through an acute percutaneous tract may be associated with complications.

Original languageEnglish (US)
Pages (from-to)627-630
Number of pages4
JournalInvestigative Radiology
Issue number6
StatePublished - Jun 1990


  • Cholelitbiasis
  • Choleystostomy
  • Lithotripsy laser

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

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