Performance improvements of imaging-based screening tests

Cesare Hassan, Perry J. Pickhardt, Douglas Rex

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Endoscopic and radiologic tests appear to be more accurate than stool-tests in detecting advanced neoplasia because of direct visualisation of colorectal mucosa. Further technological advances are expected to improve the performance and acceptability of these tests. Several attempts at increasing the adenoma detection rate of colonoscopy have been tested, and in vivo histologic differentiation between neoplastic and hyperplastic polyps may lead to substantial saving in economic and medical resources. Low-volume and non-cathartic bowel preparations may improve CT colonography acceptability, whilst computer-aided detection and low-dose protocols may result in a higher accuracy and safety of this procedure. Despite the lack of ionising radiation, significant drawbacks will likely to limit the role of MR colonography in screening programs. Colon capsule endoscopy appears to be a safe and technically feasible procedure. The suboptimal accuracy of the first generation seems to be substantially improved by the second generation of this device.

Original languageEnglish
Pages (from-to)493-507
Number of pages15
JournalBest Practice and Research: Clinical Gastroenterology
Volume24
Issue number4
DOIs
StatePublished - Aug 2010

Fingerprint

Computed Tomographic Colonography
Capsule Endoscopy
Medical Economics
Colonoscopy
Polyps
Ionizing Radiation
Adenoma
Colon
Mucous Membrane
Safety
Equipment and Supplies
Neoplasms

Keywords

  • Colon capsule endoscopy
  • Colonoscopy
  • Colorectal cancer screening
  • CT colonography
  • MR colonography

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Performance improvements of imaging-based screening tests. / Hassan, Cesare; Pickhardt, Perry J.; Rex, Douglas.

In: Best Practice and Research: Clinical Gastroenterology, Vol. 24, No. 4, 08.2010, p. 493-507.

Research output: Contribution to journalArticle

Hassan, Cesare ; Pickhardt, Perry J. ; Rex, Douglas. / Performance improvements of imaging-based screening tests. In: Best Practice and Research: Clinical Gastroenterology. 2010 ; Vol. 24, No. 4. pp. 493-507.
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