Performance of sphincter of oddi manometry

Evan L. Fogel, Stuart Sherman, Lois Bucksot, Lee Ann Shelly, Glen A. Lehman

Research output: Contribution to journalArticle

3 Scopus citations


The sphincter of Oddi (SO) is a complex smooth muscle structure surrounding the terminal common bile duct, main pancreatic duct, and common channel, when present (Figure 1). The high-pressure zone generated by the sphincter varies from 4-10 mm in length. The SO regulates the flow of bile and pancreatic exocrine juice and prevents duodenum-to-duct reflux, maintaining a sterile intraductal environment. The SO possesses basal pressure and phasic contractile activities; the former is the predominant mechanism regulating flow of pancreatobiliary secretions. The phasic SO contractions, though aiding in emission of bile and pancreatic juices, primarily function to prevent intraductal infection.

Original languageEnglish (US)
Pages (from-to)165-173
Number of pages9
JournalClinical Perspectives in Gastroenterology
Issue number3
StatePublished - Jan 1 2001

ASJC Scopus subject areas

  • Gastroenterology

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