Pericentric X inversion in dizygotic twins who differ in X chromosome inactivation and menstrual cycle function

Elisabeth A. Keitges, Catherine G. Palmer, David Weaver

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

A 21-year-old female dizygotic twin was referred for cytogenetic evaluation because of mild mental retardation. Significant history, clinical, and physical findings included irregular menses, mildly coarse facies, and microcornea. Chromosome analysis revealed a pericentric inversion of the X chromosome, 46,X,inv(X)(p11;q22). Her twin who is phenotypically normal was also found to carry the same inversion. The twins differ significantly in X chromosome inactivation and menstrual cycle function.

Original languageEnglish
Pages (from-to)210-213
Number of pages4
JournalHuman Genetics
Volume62
Issue number3
DOIs
StatePublished - Dec 1982

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Dizygotic Twins
X Chromosome Inactivation
Menstrual Cycle
Menstruation
X Chromosome
Cytogenetics
Intellectual Disability
Chromosomes
History

ASJC Scopus subject areas

  • Genetics(clinical)
  • Genetics

Cite this

Pericentric X inversion in dizygotic twins who differ in X chromosome inactivation and menstrual cycle function. / Keitges, Elisabeth A.; Palmer, Catherine G.; Weaver, David.

In: Human Genetics, Vol. 62, No. 3, 12.1982, p. 210-213.

Research output: Contribution to journalArticle

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