Perinatal outcome in the live-born infant with prenatally diagnosed omphalocele

Michelle A. Kominiarek, Noelia Zork, Sara Michelle Pierce, Terrell Zollinger

    Research output: Contribution to journalArticle

    9 Citations (Scopus)

    Abstract

    We compared perinatal outcomes between live-born nonisolated and isolated omphaloceles diagnosed during a prenatal ultrasound. Fetuses (n=86) with omphalocele were identified between 1995 and 2007 at a single institution. Inclusion criteria were an omphalocele >14 weeks' gestation, available fetal and/or neonatal karyotype, and a live-born infant (n=46). Perinatal outcomes were compared in nonisolated (n=23) and isolated omphaloceles (n=23). For all omphaloceles, the majority delivered after 34 weeks by cesarean. Mean birth weight (2782 versus 2704 g), median length of stay (27 versus 25 days), and mortality (two deaths in each group) were not different between the nonisolated and isolated groups (p>0.05). In the nonisolated group, seven major anomalies were not confirmed postnatally. Of the prenatally diagnosed isolated omphaloceles, 8 (35%) were diagnosed with a syndrome or other anomalies after birth. The outcomes were similar in nonisolated and isolated prenatally diagnosed omphaloceles, but ultrasound did not always accurately determine the presence or absence of associated anomalies.

    Original languageEnglish
    Pages (from-to)627-633
    Number of pages7
    JournalAmerican Journal of Perinatology
    Volume28
    Issue number8
    DOIs
    StatePublished - 2011

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    Umbilical Hernia
    Karyotype
    Birth Weight
    Length of Stay
    Fetus
    Parturition
    Pregnancy
    Mortality

    Keywords

    • Omphalocele
    • perinatal outcome
    • prenatal diagnosis

    ASJC Scopus subject areas

    • Pediatrics, Perinatology, and Child Health
    • Obstetrics and Gynecology

    Cite this

    Perinatal outcome in the live-born infant with prenatally diagnosed omphalocele. / Kominiarek, Michelle A.; Zork, Noelia; Pierce, Sara Michelle; Zollinger, Terrell.

    In: American Journal of Perinatology, Vol. 28, No. 8, 2011, p. 627-633.

    Research output: Contribution to journalArticle

    Kominiarek, Michelle A. ; Zork, Noelia ; Pierce, Sara Michelle ; Zollinger, Terrell. / Perinatal outcome in the live-born infant with prenatally diagnosed omphalocele. In: American Journal of Perinatology. 2011 ; Vol. 28, No. 8. pp. 627-633.
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