Perinatal outcomes and hospital costs in gastroschisis based on gestational age at delivery

Mary Ashley Cain, Jason L. Salemi, Jean Paul Tanner, Mulubrhan F. Mogos, Russell S. Kirby, Valerie E. Whiteman, Hamisu M. Salihu

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

OBJECTIVE: To investigate the association between gestational age at delivery and perinatal outcomes among gastroschisis-affected pregnancies that result in live birth. METHODS: We conducted a retrospective cohort study using a linked maternal-infant database for more than 2.3 million liveborn neonates in Florida from 1998 to 2009. Cases were identified using a combination of International Classification of Diseases, 9th Edition, Clinical Modification, diagnosis and procedure codes indicative of gastroschisis. We restricted our analyses to singleton cases without another major birth defect or medical conditions that would justify early elective delivery. We categorized cases based on gestational age in weeks and compared perinatal outcomes. RESULTS: Among 1,005 neonates with gastroschisis, 324 (32.3%) were isolated, singleton cases without an additional indication for early delivery. We observed decreased rates of adverse pregnancy outcomes among those neonates delivered in the early term period (37-38 weeks of gestation) compared with preterm (less than 34 weeks of gestation); specifically, jaundice (18.5% compared with 42.3%, P=.01) and respiratory distress syndrome (5.9% compared with 23.1%, P≤01). As the gestational age at birth increased, we observed fewer mean number of days spent in the hospital (less than 34 weeks of gestation: 55.9, P

Original languageEnglish (US)
Pages (from-to)543-550
Number of pages8
JournalObstetrics and Gynecology
Volume124
Issue number3
DOIs
StatePublished - 2014
Externally publishedYes

Fingerprint

Gastroschisis
Hospital Costs
Gestational Age
Pregnancy
Newborn Infant
Live Birth
International Classification of Diseases
Pregnancy Outcome
Jaundice
Cohort Studies
Retrospective Studies
Mothers
Parturition
Databases

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Medicine(all)

Cite this

Cain, M. A., Salemi, J. L., Tanner, J. P., Mogos, M. F., Kirby, R. S., Whiteman, V. E., & Salihu, H. M. (2014). Perinatal outcomes and hospital costs in gastroschisis based on gestational age at delivery. Obstetrics and Gynecology, 124(3), 543-550. https://doi.org/10.1097/AOG.0000000000000427

Perinatal outcomes and hospital costs in gastroschisis based on gestational age at delivery. / Cain, Mary Ashley; Salemi, Jason L.; Tanner, Jean Paul; Mogos, Mulubrhan F.; Kirby, Russell S.; Whiteman, Valerie E.; Salihu, Hamisu M.

In: Obstetrics and Gynecology, Vol. 124, No. 3, 2014, p. 543-550.

Research output: Contribution to journalArticle

Cain, MA, Salemi, JL, Tanner, JP, Mogos, MF, Kirby, RS, Whiteman, VE & Salihu, HM 2014, 'Perinatal outcomes and hospital costs in gastroschisis based on gestational age at delivery', Obstetrics and Gynecology, vol. 124, no. 3, pp. 543-550. https://doi.org/10.1097/AOG.0000000000000427
Cain, Mary Ashley ; Salemi, Jason L. ; Tanner, Jean Paul ; Mogos, Mulubrhan F. ; Kirby, Russell S. ; Whiteman, Valerie E. ; Salihu, Hamisu M. / Perinatal outcomes and hospital costs in gastroschisis based on gestational age at delivery. In: Obstetrics and Gynecology. 2014 ; Vol. 124, No. 3. pp. 543-550.
@article{16c00b0251604a469d5d87da4d81b029,
title = "Perinatal outcomes and hospital costs in gastroschisis based on gestational age at delivery",
abstract = "OBJECTIVE: To investigate the association between gestational age at delivery and perinatal outcomes among gastroschisis-affected pregnancies that result in live birth. METHODS: We conducted a retrospective cohort study using a linked maternal-infant database for more than 2.3 million liveborn neonates in Florida from 1998 to 2009. Cases were identified using a combination of International Classification of Diseases, 9th Edition, Clinical Modification, diagnosis and procedure codes indicative of gastroschisis. We restricted our analyses to singleton cases without another major birth defect or medical conditions that would justify early elective delivery. We categorized cases based on gestational age in weeks and compared perinatal outcomes. RESULTS: Among 1,005 neonates with gastroschisis, 324 (32.3{\%}) were isolated, singleton cases without an additional indication for early delivery. We observed decreased rates of adverse pregnancy outcomes among those neonates delivered in the early term period (37-38 weeks of gestation) compared with preterm (less than 34 weeks of gestation); specifically, jaundice (18.5{\%} compared with 42.3{\%}, P=.01) and respiratory distress syndrome (5.9{\%} compared with 23.1{\%}, P≤01). As the gestational age at birth increased, we observed fewer mean number of days spent in the hospital (less than 34 weeks of gestation: 55.9, P",
author = "Cain, {Mary Ashley} and Salemi, {Jason L.} and Tanner, {Jean Paul} and Mogos, {Mulubrhan F.} and Kirby, {Russell S.} and Whiteman, {Valerie E.} and Salihu, {Hamisu M.}",
year = "2014",
doi = "10.1097/AOG.0000000000000427",
language = "English (US)",
volume = "124",
pages = "543--550",
journal = "Obstetrics and Gynecology",
issn = "0029-7844",
publisher = "Lippincott Williams and Wilkins",
number = "3",

}

TY - JOUR

T1 - Perinatal outcomes and hospital costs in gastroschisis based on gestational age at delivery

AU - Cain, Mary Ashley

AU - Salemi, Jason L.

AU - Tanner, Jean Paul

AU - Mogos, Mulubrhan F.

AU - Kirby, Russell S.

AU - Whiteman, Valerie E.

AU - Salihu, Hamisu M.

PY - 2014

Y1 - 2014

N2 - OBJECTIVE: To investigate the association between gestational age at delivery and perinatal outcomes among gastroschisis-affected pregnancies that result in live birth. METHODS: We conducted a retrospective cohort study using a linked maternal-infant database for more than 2.3 million liveborn neonates in Florida from 1998 to 2009. Cases were identified using a combination of International Classification of Diseases, 9th Edition, Clinical Modification, diagnosis and procedure codes indicative of gastroschisis. We restricted our analyses to singleton cases without another major birth defect or medical conditions that would justify early elective delivery. We categorized cases based on gestational age in weeks and compared perinatal outcomes. RESULTS: Among 1,005 neonates with gastroschisis, 324 (32.3%) were isolated, singleton cases without an additional indication for early delivery. We observed decreased rates of adverse pregnancy outcomes among those neonates delivered in the early term period (37-38 weeks of gestation) compared with preterm (less than 34 weeks of gestation); specifically, jaundice (18.5% compared with 42.3%, P=.01) and respiratory distress syndrome (5.9% compared with 23.1%, P≤01). As the gestational age at birth increased, we observed fewer mean number of days spent in the hospital (less than 34 weeks of gestation: 55.9, P

AB - OBJECTIVE: To investigate the association between gestational age at delivery and perinatal outcomes among gastroschisis-affected pregnancies that result in live birth. METHODS: We conducted a retrospective cohort study using a linked maternal-infant database for more than 2.3 million liveborn neonates in Florida from 1998 to 2009. Cases were identified using a combination of International Classification of Diseases, 9th Edition, Clinical Modification, diagnosis and procedure codes indicative of gastroschisis. We restricted our analyses to singleton cases without another major birth defect or medical conditions that would justify early elective delivery. We categorized cases based on gestational age in weeks and compared perinatal outcomes. RESULTS: Among 1,005 neonates with gastroschisis, 324 (32.3%) were isolated, singleton cases without an additional indication for early delivery. We observed decreased rates of adverse pregnancy outcomes among those neonates delivered in the early term period (37-38 weeks of gestation) compared with preterm (less than 34 weeks of gestation); specifically, jaundice (18.5% compared with 42.3%, P=.01) and respiratory distress syndrome (5.9% compared with 23.1%, P≤01). As the gestational age at birth increased, we observed fewer mean number of days spent in the hospital (less than 34 weeks of gestation: 55.9, P

UR - http://www.scopus.com/inward/record.url?scp=84925546159&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84925546159&partnerID=8YFLogxK

U2 - 10.1097/AOG.0000000000000427

DO - 10.1097/AOG.0000000000000427

M3 - Article

C2 - 25162254

AN - SCOPUS:84925546159

VL - 124

SP - 543

EP - 550

JO - Obstetrics and Gynecology

JF - Obstetrics and Gynecology

SN - 0029-7844

IS - 3

ER -