Perinatal Stroke in Twins Without Co-twin Demise

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Perinatal stroke in twins without co-twin demise has not been well-described. In this study, the International Classification of Diseases- 9th edition code searches and medical record review were used to identify all children with arterial ischemic stroke examined in a pediatric stroke clinic over a 2-year period. Four of the 35 children (11.4%) with perinatal arterial ischemic stroke were twins; none had co-twin demise. No co-twin had any clinical evidence of perinatal stroke. The most common findings on prothrombotic evaluation were elevated antiphospholipid antibodies (2), elevated lipoprotein a (2), and elevated Factor VIIIc (2). Twin gestation without co-twin demise may be a risk factor for perinatal stroke, and might help explain the higher incidence of cerebral palsy in twins.

Original languageEnglish
Pages (from-to)75-77
Number of pages3
JournalPediatric Neurology
Volume35
Issue number1
DOIs
StatePublished - Jul 2006

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Stroke
Antiphospholipid Antibodies
Lipoprotein(a)
International Classification of Diseases
Cerebral Palsy
Medical Records
Pediatrics
Pregnancy
Incidence

ASJC Scopus subject areas

  • Clinical Neurology
  • Pediatrics, Perinatology, and Child Health
  • Developmental Neuroscience
  • Neurology

Cite this

Perinatal Stroke in Twins Without Co-twin Demise. / Golomb, Meredith; Williams, Linda; Garg, Bhuwan P.

In: Pediatric Neurology, Vol. 35, No. 1, 07.2006, p. 75-77.

Research output: Contribution to journalArticle

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