Periodontal disease and systemic disease. Clinical information for the practicing dentist.

Vanchit John, Seok Jin Kim

Research output: Contribution to journalReview article

3 Scopus citations


The relationship between periodontal and systemic disease, previously called the "focal infection theory" or "focus of infection," has become an exciting area of clinical and laboratory research. Periodontal disease has been reported to influence diabetes mellitus, cardiovascular disease, osteoporosis, and respiratory disease. It also can influence the course and duration of pregnancy. This article reviews some of these associations and proposed mechanisms by which periodontal disease and systemic conditions influence each other. We also discuss clinical implications for our daily practice in dentistry.

Original languageEnglish (US)
Pages (from-to)15-18
Number of pages4
JournalJournal (Indiana Dental Association)
Issue number2
StatePublished - Jan 1 2002


ASJC Scopus subject areas

  • Medicine(all)

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