Peripheral mechanisms affecting the lower esophageal sphincter tone

Samer Gawrieh, Reza Shaker

Research output: Contribution to journalReview article

5 Citations (Scopus)

Abstract

LES tone is influenced by central and peripheral mechanisms. Peripheral factors influencing the LES tone include inhibitory reflexes originating from the stomach, esophagus, pharynx, and larynx. Although the role of LES relaxation and its associated reflux events induced by gastric distention has been extensively studied, the LES relaxations triggered by stimulation of the aerodigestive tract have only recently been the focus of systematic investigation and have resulted in documentation of the intricate reflex relationship between the upper gastrointestinal tract and the aerodigestive tract.

Original languageEnglish (US)
JournalGastroenterology Clinics of North America
Volume31
Issue number4 SUPPL.
StatePublished - Dec 2002
Externally publishedYes

Fingerprint

Lower Esophageal Sphincter
Reflex
Stomach
Upper Gastrointestinal Tract
Larynx
Pharynx
Documentation
Esophagus

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Peripheral mechanisms affecting the lower esophageal sphincter tone. / Gawrieh, Samer; Shaker, Reza.

In: Gastroenterology Clinics of North America, Vol. 31, No. 4 SUPPL., 12.2002.

Research output: Contribution to journalReview article

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