Peripheral precocious puberty: Causes and current management

Research output: Contribution to journalArticle

24 Scopus citations


Background: Peripheral precocious puberty (PPP) results from sex steroid exposure by a process other than activation of the hypothalamic-pituitary- gonadal axis. It is much less common than central precocious puberty and may be congenital or acquired. Causes of PPP range from well-characterized genetic mutations to those conditions without a known etiology (idiopathic). Medical evaluation and treatment of affected children is guided by the presenting features and ultimate diagnosis. Conclusions: Carefully executed and collaborative multicenter investigations are essential to expand our knowledge of the underlying pathophysiology, optimal therapy and ultimate outcomes in children with PPP.

Original languageEnglish (US)
Pages (from-to)64-67
Number of pages4
JournalHormone Research
Issue numberSUPPL. 1
StatePublished - Jan 1 2009


  • Familial male-limited precocious puberty
  • McCune-Albright syndrome
  • Precocious puberty

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

Fingerprint Dive into the research topics of 'Peripheral precocious puberty: Causes and current management'. Together they form a unique fingerprint.

  • Cite this