Peripheral precocious puberty including congenital adrenal hyperplasia

causes, consequences, management and outcomes

Nadine G. Haddad, Erica Eugster

Research output: Contribution to journalReview article

Abstract

Peripheral precocious puberty results from peripheral production of sex steroids independent of activation of the hypothalamic-pituitary gonadal axis. It is much less common than central precocious puberty. Causes are variable and can be congenital or acquired. In this review, we will discuss the diagnosis and management of the most common etiologies including congenital adrenal hyperplasia, McCune Albright syndrome, familial male-limited precocious puberty, and adrenal and gonadal tumors.

Original languageEnglish (US)
JournalBest Practice and Research: Clinical Endocrinology and Metabolism
DOIs
StatePublished - Jan 1 2019
Externally publishedYes

Fingerprint

Polyostotic Fibrous Dysplasia
Precocious Puberty
Congenital Adrenal Hyperplasia
Steroids
Neoplasms
Central Precocious Puberty
Familial Testotoxicosis

Keywords

  • adrenal tumors
  • congenital adrenal hyperplasia
  • familial male-limited precocious puberty
  • gonadal tumors
  • McCune Albright syndrome
  • peripheral precocious puberty

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

Cite this

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abstract = "Peripheral precocious puberty results from peripheral production of sex steroids independent of activation of the hypothalamic-pituitary gonadal axis. It is much less common than central precocious puberty. Causes are variable and can be congenital or acquired. In this review, we will discuss the diagnosis and management of the most common etiologies including congenital adrenal hyperplasia, McCune Albright syndrome, familial male-limited precocious puberty, and adrenal and gonadal tumors.",
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