Persistence of cyclosporine after withdrawal of the drug in a patient with chronic liver transplant rejection: Role of the monoethylglycinexylidine test

Rahul M. Jindal, Mark D. Pescovitz, Oscar Cummings, Benita Book, Lawrence Lumeng, Martin L. Milgrom, Stephen B. Leapman, Ronald S. Filo

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Patients with chronic rejection of liver allografts may show persistently high cyclosporine levels. This phenomenon may be due to a down-regulation of the P450 cytochrome system. The monoethylglycinexylidine test was useful in confirming this hypothesis.

Original languageEnglish
Pages (from-to)1657-1658
Number of pages2
JournalTransplantation
Volume61
Issue number11
StatePublished - Jun 15 1996

Fingerprint

Graft Rejection
Cytochrome P-450 Enzyme System
Cyclosporine
Allografts
Down-Regulation
Liver
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Transplantation
  • Immunology

Cite this

Persistence of cyclosporine after withdrawal of the drug in a patient with chronic liver transplant rejection : Role of the monoethylglycinexylidine test. / Jindal, Rahul M.; Pescovitz, Mark D.; Cummings, Oscar; Book, Benita; Lumeng, Lawrence; Milgrom, Martin L.; Leapman, Stephen B.; Filo, Ronald S.

In: Transplantation, Vol. 61, No. 11, 15.06.1996, p. 1657-1658.

Research output: Contribution to journalArticle

Jindal, RM, Pescovitz, MD, Cummings, O, Book, B, Lumeng, L, Milgrom, ML, Leapman, SB & Filo, RS 1996, 'Persistence of cyclosporine after withdrawal of the drug in a patient with chronic liver transplant rejection: Role of the monoethylglycinexylidine test', Transplantation, vol. 61, no. 11, pp. 1657-1658.
Jindal, Rahul M. ; Pescovitz, Mark D. ; Cummings, Oscar ; Book, Benita ; Lumeng, Lawrence ; Milgrom, Martin L. ; Leapman, Stephen B. ; Filo, Ronald S. / Persistence of cyclosporine after withdrawal of the drug in a patient with chronic liver transplant rejection : Role of the monoethylglycinexylidine test. In: Transplantation. 1996 ; Vol. 61, No. 11. pp. 1657-1658.
@article{b407a0ce6fa542bbb3d1d2c1a9be20a0,
title = "Persistence of cyclosporine after withdrawal of the drug in a patient with chronic liver transplant rejection: Role of the monoethylglycinexylidine test",
abstract = "Patients with chronic rejection of liver allografts may show persistently high cyclosporine levels. This phenomenon may be due to a down-regulation of the P450 cytochrome system. The monoethylglycinexylidine test was useful in confirming this hypothesis.",
author = "Jindal, {Rahul M.} and Pescovitz, {Mark D.} and Oscar Cummings and Benita Book and Lawrence Lumeng and Milgrom, {Martin L.} and Leapman, {Stephen B.} and Filo, {Ronald S.}",
year = "1996",
month = "6",
day = "15",
language = "English",
volume = "61",
pages = "1657--1658",
journal = "Transplantation",
issn = "0041-1337",
publisher = "Lippincott Williams and Wilkins",
number = "11",

}

TY - JOUR

T1 - Persistence of cyclosporine after withdrawal of the drug in a patient with chronic liver transplant rejection

T2 - Role of the monoethylglycinexylidine test

AU - Jindal, Rahul M.

AU - Pescovitz, Mark D.

AU - Cummings, Oscar

AU - Book, Benita

AU - Lumeng, Lawrence

AU - Milgrom, Martin L.

AU - Leapman, Stephen B.

AU - Filo, Ronald S.

PY - 1996/6/15

Y1 - 1996/6/15

N2 - Patients with chronic rejection of liver allografts may show persistently high cyclosporine levels. This phenomenon may be due to a down-regulation of the P450 cytochrome system. The monoethylglycinexylidine test was useful in confirming this hypothesis.

AB - Patients with chronic rejection of liver allografts may show persistently high cyclosporine levels. This phenomenon may be due to a down-regulation of the P450 cytochrome system. The monoethylglycinexylidine test was useful in confirming this hypothesis.

UR - http://www.scopus.com/inward/record.url?scp=0029898555&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029898555&partnerID=8YFLogxK

M3 - Article

C2 - 8669116

AN - SCOPUS:0029898555

VL - 61

SP - 1657

EP - 1658

JO - Transplantation

JF - Transplantation

SN - 0041-1337

IS - 11

ER -