Abstract
Context: The public health implications of depression and cognitive impairment in late life are enormous. Cognitive impairment and late-life depression are associated with increased risk for subsequent dementia; however, investigations of these phenomena appear to be proceeding along separate tracks. Objectives and Data Source: The National Institute of Mental Health organized the conference "Perspectives on Depression, Mild Cognitive Impairment, and Cognitive Decline" to consider how the varied perspectives might be better integrated to examine the associations among depression, mild cognitive impairment, and cognitive decline and to illuminate the common or distinct mechanisms involved in these associations. Data Synthesis: The following 2 broad questions were addressed: (1) What gaps in our knowledge have the greatest public health significance? (2) Can we more efficiently use our research dollars and participant resources to fill these gaps? Meeting participants included grantees from the National Institute of Mental Health and the National Institute on Aging and program staff from the National Institute of Mental Health, the National Institute on Aging, and the National Institute of Neurological Disorders and Stroke. Conclusions: One of the most important recommendations to emerge from the meeting discussions is for increased collaboration among clinical and epidemiological investigators whose work focuses in the area of depression with those working primarily in the area of memory disorders. Directions for future research were identified.
| Original language | English |
|---|---|
| Pages (from-to) | 130-138 |
| Number of pages | 9 |
| Journal | Archives of General Psychiatry |
| Volume | 63 |
| Issue number | 2 |
| DOIs | |
| State | Published - Feb 2006 |
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ASJC Scopus subject areas
- Psychiatry and Mental health
Cite this
Perspectives on depression, mild cognitive impairment, and cognitive decline. / Steffens, David C.; Otey, Emeline; Alexopoulos, George S.; Butters, Meryl A.; Cuthbert, Bruce; Ganguli, Mary; Geda, Yonas E.; Hendrie, Hugh; Krishnan, Ranga R.; Kumar, Anand; Lopez, Oscar L.; Lyketsos, Constantine G.; Mast, Benjamin T.; Morris, John C.; Norton, Maria C.; Peavy, Guerry M.; Petersen, Ronald C.; Reynolds, Charles F.; Salloway, Stephen; Welsh-Bohmer, Kathleen A.; Yesavage, Jerome.
In: Archives of General Psychiatry, Vol. 63, No. 2, 02.2006, p. 130-138.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Perspectives on depression, mild cognitive impairment, and cognitive decline
AU - Steffens, David C.
AU - Otey, Emeline
AU - Alexopoulos, George S.
AU - Butters, Meryl A.
AU - Cuthbert, Bruce
AU - Ganguli, Mary
AU - Geda, Yonas E.
AU - Hendrie, Hugh
AU - Krishnan, Ranga R.
AU - Kumar, Anand
AU - Lopez, Oscar L.
AU - Lyketsos, Constantine G.
AU - Mast, Benjamin T.
AU - Morris, John C.
AU - Norton, Maria C.
AU - Peavy, Guerry M.
AU - Petersen, Ronald C.
AU - Reynolds, Charles F.
AU - Salloway, Stephen
AU - Welsh-Bohmer, Kathleen A.
AU - Yesavage, Jerome
PY - 2006/2
Y1 - 2006/2
N2 - Context: The public health implications of depression and cognitive impairment in late life are enormous. Cognitive impairment and late-life depression are associated with increased risk for subsequent dementia; however, investigations of these phenomena appear to be proceeding along separate tracks. Objectives and Data Source: The National Institute of Mental Health organized the conference "Perspectives on Depression, Mild Cognitive Impairment, and Cognitive Decline" to consider how the varied perspectives might be better integrated to examine the associations among depression, mild cognitive impairment, and cognitive decline and to illuminate the common or distinct mechanisms involved in these associations. Data Synthesis: The following 2 broad questions were addressed: (1) What gaps in our knowledge have the greatest public health significance? (2) Can we more efficiently use our research dollars and participant resources to fill these gaps? Meeting participants included grantees from the National Institute of Mental Health and the National Institute on Aging and program staff from the National Institute of Mental Health, the National Institute on Aging, and the National Institute of Neurological Disorders and Stroke. Conclusions: One of the most important recommendations to emerge from the meeting discussions is for increased collaboration among clinical and epidemiological investigators whose work focuses in the area of depression with those working primarily in the area of memory disorders. Directions for future research were identified.
AB - Context: The public health implications of depression and cognitive impairment in late life are enormous. Cognitive impairment and late-life depression are associated with increased risk for subsequent dementia; however, investigations of these phenomena appear to be proceeding along separate tracks. Objectives and Data Source: The National Institute of Mental Health organized the conference "Perspectives on Depression, Mild Cognitive Impairment, and Cognitive Decline" to consider how the varied perspectives might be better integrated to examine the associations among depression, mild cognitive impairment, and cognitive decline and to illuminate the common or distinct mechanisms involved in these associations. Data Synthesis: The following 2 broad questions were addressed: (1) What gaps in our knowledge have the greatest public health significance? (2) Can we more efficiently use our research dollars and participant resources to fill these gaps? Meeting participants included grantees from the National Institute of Mental Health and the National Institute on Aging and program staff from the National Institute of Mental Health, the National Institute on Aging, and the National Institute of Neurological Disorders and Stroke. Conclusions: One of the most important recommendations to emerge from the meeting discussions is for increased collaboration among clinical and epidemiological investigators whose work focuses in the area of depression with those working primarily in the area of memory disorders. Directions for future research were identified.
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UR - http://www.scopus.com/inward/citedby.url?scp=32244442311&partnerID=8YFLogxK
U2 - 10.1001/archpsyc.63.2.130
DO - 10.1001/archpsyc.63.2.130
M3 - Article
C2 - 16461855
AN - SCOPUS:32244442311
VL - 63
SP - 130
EP - 138
JO - JAMA Psychiatry
JF - JAMA Psychiatry
SN - 2168-622X
IS - 2
ER -