PET scanning and the solitary pulmonary nodule

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

The finding of a solitary pulmonary nodule on a chest radiograph is a common problem in pulmonary medicine and is seen in about 1 in 500 chest radiographs. Of the benign lesions, 80% are infectious granulomas, 10% are hamartomas, and the remaining 10% are caused by a variety of rarer disorders including noninfectious granulomas and other benign tumors. The prevalence of malignancy ranges from 10% to 68% in the literature. Because of the high prevalence of malignancy and the poor survival for lung cancer, early detection, characterization, and directed treatment are important. Positron emission tomography with 18-Fluorodeoxyglucose (FDG-PET) can play an important role in the evaluation and management of solitary pulmonary nodules. This includes improved characterization of solitary pulmonary nodules with very high negative predictive value and improved staging information when performed in association with CT, especially for nodal staging and identification of unsuspected stage IV disease. PET also provides additional information for management of solitary pulmonary nodules by esitimating the probability of malignancy.

Original languageEnglish
Pages (from-to)268-274
Number of pages7
JournalSeminars in Thoracic and Cardiovascular Surgery
Volume14
Issue number3
StatePublished - Jul 2002

Fingerprint

Solitary Pulmonary Nodule
Granuloma
Neoplasms
Thorax
Pulmonary Medicine
Information Management
Hamartoma
Positron-Emission Tomography
Lung Neoplasms

Keywords

  • 18-Fluorodeoxyglucose
  • Lung cancer
  • Positron emission tomography

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

PET scanning and the solitary pulmonary nodule. / Fletcher, James.

In: Seminars in Thoracic and Cardiovascular Surgery, Vol. 14, No. 3, 07.2002, p. 268-274.

Research output: Contribution to journalArticle

@article{af7145508acf43bcbb61a787ecaa8914,
title = "PET scanning and the solitary pulmonary nodule",
abstract = "The finding of a solitary pulmonary nodule on a chest radiograph is a common problem in pulmonary medicine and is seen in about 1 in 500 chest radiographs. Of the benign lesions, 80{\%} are infectious granulomas, 10{\%} are hamartomas, and the remaining 10{\%} are caused by a variety of rarer disorders including noninfectious granulomas and other benign tumors. The prevalence of malignancy ranges from 10{\%} to 68{\%} in the literature. Because of the high prevalence of malignancy and the poor survival for lung cancer, early detection, characterization, and directed treatment are important. Positron emission tomography with 18-Fluorodeoxyglucose (FDG-PET) can play an important role in the evaluation and management of solitary pulmonary nodules. This includes improved characterization of solitary pulmonary nodules with very high negative predictive value and improved staging information when performed in association with CT, especially for nodal staging and identification of unsuspected stage IV disease. PET also provides additional information for management of solitary pulmonary nodules by esitimating the probability of malignancy.",
keywords = "18-Fluorodeoxyglucose, Lung cancer, Positron emission tomography",
author = "James Fletcher",
year = "2002",
month = "7",
language = "English",
volume = "14",
pages = "268--274",
journal = "Seminars in Thoracic and Cardiovascular Surgery",
issn = "1043-0679",
publisher = "W.B. Saunders Ltd",
number = "3",

}

TY - JOUR

T1 - PET scanning and the solitary pulmonary nodule

AU - Fletcher, James

PY - 2002/7

Y1 - 2002/7

N2 - The finding of a solitary pulmonary nodule on a chest radiograph is a common problem in pulmonary medicine and is seen in about 1 in 500 chest radiographs. Of the benign lesions, 80% are infectious granulomas, 10% are hamartomas, and the remaining 10% are caused by a variety of rarer disorders including noninfectious granulomas and other benign tumors. The prevalence of malignancy ranges from 10% to 68% in the literature. Because of the high prevalence of malignancy and the poor survival for lung cancer, early detection, characterization, and directed treatment are important. Positron emission tomography with 18-Fluorodeoxyglucose (FDG-PET) can play an important role in the evaluation and management of solitary pulmonary nodules. This includes improved characterization of solitary pulmonary nodules with very high negative predictive value and improved staging information when performed in association with CT, especially for nodal staging and identification of unsuspected stage IV disease. PET also provides additional information for management of solitary pulmonary nodules by esitimating the probability of malignancy.

AB - The finding of a solitary pulmonary nodule on a chest radiograph is a common problem in pulmonary medicine and is seen in about 1 in 500 chest radiographs. Of the benign lesions, 80% are infectious granulomas, 10% are hamartomas, and the remaining 10% are caused by a variety of rarer disorders including noninfectious granulomas and other benign tumors. The prevalence of malignancy ranges from 10% to 68% in the literature. Because of the high prevalence of malignancy and the poor survival for lung cancer, early detection, characterization, and directed treatment are important. Positron emission tomography with 18-Fluorodeoxyglucose (FDG-PET) can play an important role in the evaluation and management of solitary pulmonary nodules. This includes improved characterization of solitary pulmonary nodules with very high negative predictive value and improved staging information when performed in association with CT, especially for nodal staging and identification of unsuspected stage IV disease. PET also provides additional information for management of solitary pulmonary nodules by esitimating the probability of malignancy.

KW - 18-Fluorodeoxyglucose

KW - Lung cancer

KW - Positron emission tomography

UR - http://www.scopus.com/inward/record.url?scp=0036656788&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036656788&partnerID=8YFLogxK

M3 - Article

C2 - 12232868

AN - SCOPUS:0036656788

VL - 14

SP - 268

EP - 274

JO - Seminars in Thoracic and Cardiovascular Surgery

JF - Seminars in Thoracic and Cardiovascular Surgery

SN - 1043-0679

IS - 3

ER -