Pharmacogenetics and individualizing drug treatment during pregnancy

Research output: Contribution to journalReview article

15 Scopus citations

Abstract

Pharmacogenetics as a tool to aid clinicians implement individualized pharmacotherapy is utilized in some areas of medicine. Pharmacogenetics in pregnancy is still a developing field. However, there are several areas of obstetric therapeutics where data are emerging that give glimpses into future therapeutic possibilities. These include opioid pain management, antihypertensive therapy, antidepressant medications, preterm labor tocolytics, antenatal corticosteroids and drugs for nausea and vomiting of pregnancy, to name a few. More data are needed to populate the therapeutic models and to truly determine if pharmacogenetics will aid in individualizing pharmacotherapy in pregnancy. The objective of this review is to summarize current data and highlight research needs.

Original languageEnglish (US)
Pages (from-to)69-78
Number of pages10
JournalPharmacogenomics
Volume15
Issue number1
DOIs
StatePublished - Jan 1 2014

Keywords

  • Pharmacogenetics
  • Pregnancy
  • Therapeutics

ASJC Scopus subject areas

  • Pharmacology
  • Genetics
  • Molecular Medicine

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