Pharmacokinetic studies in pregnant women

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The only way to determine appropriate medication dosing during pregnancy is to evaluate the pharmacokinetics and pharmacodynamics of individual medications in pregnant women. This type of clinical investigation can present a variety of challenges and concerns. This chapter summarizes what is known about physiologic changes in pregnancy and the impact these changes can have on drug disposition, and provides a model approach for completing pharmacokinetic studies in women during pregnancy.

Original languageEnglish (US)
Title of host publicationPharmacokinetics in Drug Development
PublisherSpringer US
Pages195-209
Number of pages15
Volume3
ISBN (Print)9781441979360
DOIs
StatePublished - Dec 1 2011

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ASJC Scopus subject areas

  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

Renbarger, J. L., & Haas, D. M. (2011). Pharmacokinetic studies in pregnant women. In Pharmacokinetics in Drug Development (Vol. 3, pp. 195-209). Springer US. https://doi.org/10.1007/978-1-4419-7937-7_9