Pharmacological control of gastric acid secretion.

A. M. Zfass, Lee McHenry, A. J. Sanyal

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

Gastric acid produced by the parietal cells has a significant role in a variety of gastrointestinal diseases, such as duodenal ulcer, gastric ulcer, and gastroesophageal reflux disease. We address acid production by the parietal cell and the pharmacological means to control gastric acid secretion. The physiology of parietal cell acid secretion is reviewed. The role of acid-suppressive therapy with histamine H2 antagonists and omeprazole in duodenal ulcer, gastric ulcer, and gastroesophageal reflux disease is discussed. Pharmacology, side-effect profile, and dosage requirements of the histamine H2 antagonists and omeprazole are outlined.

Original languageEnglish (US)
Pages (from-to)83-87
Number of pages5
JournalGastroenterologist
Volume1
Issue number1
StatePublished - Mar 1993
Externally publishedYes

Fingerprint

Gastric Acid
Histamine H2 Antagonists
Omeprazole
Pharmacology
Stomach Ulcer
Duodenal Ulcer
Gastroesophageal Reflux
Acids
Cell Physiological Phenomena
Gastrointestinal Diseases
Therapeutics

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Zfass, A. M., McHenry, L., & Sanyal, A. J. (1993). Pharmacological control of gastric acid secretion. Gastroenterologist, 1(1), 83-87.

Pharmacological control of gastric acid secretion. / Zfass, A. M.; McHenry, Lee; Sanyal, A. J.

In: Gastroenterologist, Vol. 1, No. 1, 03.1993, p. 83-87.

Research output: Contribution to journalReview article

Zfass, AM, McHenry, L & Sanyal, AJ 1993, 'Pharmacological control of gastric acid secretion.', Gastroenterologist, vol. 1, no. 1, pp. 83-87.
Zfass, A. M. ; McHenry, Lee ; Sanyal, A. J. / Pharmacological control of gastric acid secretion. In: Gastroenterologist. 1993 ; Vol. 1, No. 1. pp. 83-87.
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