Physical and mental health status of female adolescent/young adult survivors of breast and gynecological cancer: A national, population-based, case-control study

Celeste Phillips-Salimi, Michael A. Andrykowski

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Purpose: Each year, nearly 21,000 adolescents and young adults (AYA) ages 15 to 29 years are diagnosed with cancer. Breast and gynecological cancers account for 25 % of the cancers seen in AYA females. The purpose of this study was to compare the current physical and mental health status of female AYA cancer survivors with non-cancer female controls. Methods: Using data from the population-based 2009 National Health Interview Survey, 100 cases of female AYA survivors of breast and gynecological cancers were identified [female AYA cancer survivor (FCS) group]. FCS cases were matched with 300 female respondents without a history of cancer on age, education, marital status, and minority status [non-cancer control (NCC) group]. The FCS and NCC groups were compared on a range of physical and mental health status indices using analysis of covariance and binary logistic regression. Results: FCS group reported significantly poorer physical and mental health status than the matched controls. Relative to the NCC group, FCS survivors had significantly poorer scores on 7 of 8 mental health outcomes and were more likely to meet criteria for serious psychological distress (odds ratio = 4.23, p ≤ 0.001). FCS group also reported greater lifetime and current prevalence of various medical conditions, more health-related disabilities, and greater functional limitations than the NCC group. Conclusion: Diagnosis of breast and gynecological cancer during adolescence and young adulthood is associated with clinically important deficits in physical and mental health status. Given the young age of this cancer survivor cohort, increased attention should be devoted to minimizing these deficits.

Original languageEnglish (US)
Pages (from-to)1597-1604
Number of pages8
JournalSupportive Care in Cancer
Volume21
Issue number6
DOIs
StatePublished - Jun 2013

Fingerprint

Health Status
Survivors
Case-Control Studies
Young Adult
Mental Health
Breast Neoplasms
Population
Neoplasms
Control Groups
Health Status Indicators
Marital Status
Health Surveys
Logistic Models
Odds Ratio
Interviews
Psychology
Education
Health

Keywords

  • Adolescent/young adult
  • Breast
  • Cancer
  • Gynecological
  • Survivorship

ASJC Scopus subject areas

  • Oncology

Cite this

@article{2e3dc30b3ef34a2d8b572e67a23967f0,
title = "Physical and mental health status of female adolescent/young adult survivors of breast and gynecological cancer: A national, population-based, case-control study",
abstract = "Purpose: Each year, nearly 21,000 adolescents and young adults (AYA) ages 15 to 29 years are diagnosed with cancer. Breast and gynecological cancers account for 25 {\%} of the cancers seen in AYA females. The purpose of this study was to compare the current physical and mental health status of female AYA cancer survivors with non-cancer female controls. Methods: Using data from the population-based 2009 National Health Interview Survey, 100 cases of female AYA survivors of breast and gynecological cancers were identified [female AYA cancer survivor (FCS) group]. FCS cases were matched with 300 female respondents without a history of cancer on age, education, marital status, and minority status [non-cancer control (NCC) group]. The FCS and NCC groups were compared on a range of physical and mental health status indices using analysis of covariance and binary logistic regression. Results: FCS group reported significantly poorer physical and mental health status than the matched controls. Relative to the NCC group, FCS survivors had significantly poorer scores on 7 of 8 mental health outcomes and were more likely to meet criteria for serious psychological distress (odds ratio = 4.23, p ≤ 0.001). FCS group also reported greater lifetime and current prevalence of various medical conditions, more health-related disabilities, and greater functional limitations than the NCC group. Conclusion: Diagnosis of breast and gynecological cancer during adolescence and young adulthood is associated with clinically important deficits in physical and mental health status. Given the young age of this cancer survivor cohort, increased attention should be devoted to minimizing these deficits.",
keywords = "Adolescent/young adult, Breast, Cancer, Gynecological, Survivorship",
author = "Celeste Phillips-Salimi and Andrykowski, {Michael A.}",
year = "2013",
month = "6",
doi = "10.1007/s00520-012-1701-7",
language = "English (US)",
volume = "21",
pages = "1597--1604",
journal = "Supportive Care in Cancer",
issn = "0941-4355",
publisher = "Springer Verlag",
number = "6",

}

TY - JOUR

T1 - Physical and mental health status of female adolescent/young adult survivors of breast and gynecological cancer

T2 - A national, population-based, case-control study

AU - Phillips-Salimi, Celeste

AU - Andrykowski, Michael A.

PY - 2013/6

Y1 - 2013/6

N2 - Purpose: Each year, nearly 21,000 adolescents and young adults (AYA) ages 15 to 29 years are diagnosed with cancer. Breast and gynecological cancers account for 25 % of the cancers seen in AYA females. The purpose of this study was to compare the current physical and mental health status of female AYA cancer survivors with non-cancer female controls. Methods: Using data from the population-based 2009 National Health Interview Survey, 100 cases of female AYA survivors of breast and gynecological cancers were identified [female AYA cancer survivor (FCS) group]. FCS cases were matched with 300 female respondents without a history of cancer on age, education, marital status, and minority status [non-cancer control (NCC) group]. The FCS and NCC groups were compared on a range of physical and mental health status indices using analysis of covariance and binary logistic regression. Results: FCS group reported significantly poorer physical and mental health status than the matched controls. Relative to the NCC group, FCS survivors had significantly poorer scores on 7 of 8 mental health outcomes and were more likely to meet criteria for serious psychological distress (odds ratio = 4.23, p ≤ 0.001). FCS group also reported greater lifetime and current prevalence of various medical conditions, more health-related disabilities, and greater functional limitations than the NCC group. Conclusion: Diagnosis of breast and gynecological cancer during adolescence and young adulthood is associated with clinically important deficits in physical and mental health status. Given the young age of this cancer survivor cohort, increased attention should be devoted to minimizing these deficits.

AB - Purpose: Each year, nearly 21,000 adolescents and young adults (AYA) ages 15 to 29 years are diagnosed with cancer. Breast and gynecological cancers account for 25 % of the cancers seen in AYA females. The purpose of this study was to compare the current physical and mental health status of female AYA cancer survivors with non-cancer female controls. Methods: Using data from the population-based 2009 National Health Interview Survey, 100 cases of female AYA survivors of breast and gynecological cancers were identified [female AYA cancer survivor (FCS) group]. FCS cases were matched with 300 female respondents without a history of cancer on age, education, marital status, and minority status [non-cancer control (NCC) group]. The FCS and NCC groups were compared on a range of physical and mental health status indices using analysis of covariance and binary logistic regression. Results: FCS group reported significantly poorer physical and mental health status than the matched controls. Relative to the NCC group, FCS survivors had significantly poorer scores on 7 of 8 mental health outcomes and were more likely to meet criteria for serious psychological distress (odds ratio = 4.23, p ≤ 0.001). FCS group also reported greater lifetime and current prevalence of various medical conditions, more health-related disabilities, and greater functional limitations than the NCC group. Conclusion: Diagnosis of breast and gynecological cancer during adolescence and young adulthood is associated with clinically important deficits in physical and mental health status. Given the young age of this cancer survivor cohort, increased attention should be devoted to minimizing these deficits.

KW - Adolescent/young adult

KW - Breast

KW - Cancer

KW - Gynecological

KW - Survivorship

UR - http://www.scopus.com/inward/record.url?scp=84879182720&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84879182720&partnerID=8YFLogxK

U2 - 10.1007/s00520-012-1701-7

DO - 10.1007/s00520-012-1701-7

M3 - Article

C2 - 23306935

AN - SCOPUS:84879182720

VL - 21

SP - 1597

EP - 1604

JO - Supportive Care in Cancer

JF - Supportive Care in Cancer

SN - 0941-4355

IS - 6

ER -