Pilot study of a point-of-use decision support tool for cancer clinical trials eligibility

Philip P. Breitfeld, Marina Weisburd, J. Marc Overhage, George Sledge, William M. Tierney

Research output: Contribution to journalArticle

32 Scopus citations


Many adults with cancer are not enrolled in clinical trials because caregivers do not have the time to match the patient's clinical findings with varying eligibility criteria associated with multiple trials for which the patient might be eligible. The authors developed a point-of-use portable decision support tool (DS-TRIEL) to automate this matching process. The support tool consists of a hand-held computer with a programmable relational database. A two-level hierarchic decision framework was used for the identification of eligible subjects for two open breast cancer clinical trials. The hand-held computer also provides protocol consent forms and schemas to further help the busy oncologist. This decision support tool and the decision framework on which it is based could be used for multiple trials and different cancer sites.

Original languageEnglish (US)
Pages (from-to)466-477
Number of pages12
JournalJournal of the American Medical Informatics Association
Issue number6
StatePublished - 1999

ASJC Scopus subject areas

  • Health Informatics

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