PLASMA 25-HYDROXYVITAMIN D IN PREGNANT ASIAN WOMEN AND THEIR BABIES

John Z. Heckmatt, Ann E.J. Davies, Munro Peacock, Jennifer Mcmurray, David M. Isherwood

Research output: Contribution to journalArticle

59 Scopus citations

Abstract

Plasma 25-hydroxyvitamin D (25-OHD) was measured in cord blood taken at delivery and in fasting blood taken from 44 Asian mothers in the first day of the puerperium. Blood was taken from the baby 48 h after delivery. Cord-blood samples were also taken at 43 non-Asian deliveries. Plasma 25-OHD concentrations in Asians were low at delivery; in 81% of the mothers and 36% of the babies plasma 25-OHD was in the osteomalacic range. Asian cord-blood 25-OHD concentrations were significantly lower than concentrations in non-Asian controls. 4 Asian babies had craniotabes and 1 had neonatal tetany. 1 non-Asian baby had craniotabes. A review of 3327 deliveries in 1978 confirmed that neonatal tetany was significantly more common in Asian babies (2·3%) than in non-Asian babies (0·03%). In 44 other Asian mothers supplements of 1000 units of vitamin D daily during pregnancy significantly increased plasma-25-OHD concentrations at delivery.

Original languageEnglish (US)
Pages (from-to)546-549
Number of pages4
JournalThe Lancet
Volume314
Issue number8142
DOIs
StatePublished - Sep 15 1979

ASJC Scopus subject areas

  • Medicine(all)

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    Heckmatt, J. Z., Davies, A. E. J., Peacock, M., Mcmurray, J., & Isherwood, D. M. (1979). PLASMA 25-HYDROXYVITAMIN D IN PREGNANT ASIAN WOMEN AND THEIR BABIES. The Lancet, 314(8142), 546-549. https://doi.org/10.1016/S0140-6736(79)91612-X