Recent years have seen advances in our understanding the molecular cell biology, signaling and pathogenesis of one of the most common life-threatening genetic diseases - polycystic kidney disease (PKD). This multichapter work from international experts opens with chapters exploring the pathogenesis and pathophysiology of autosomal dominant and autosomal recessive PKD. There follows a series of chapters reflecting clinical presentations and complications of PKD, including areas such as pain management and PKD-associated hypertension. This through work concludes with coverage of clinical trials and preclinical studies underway and represents an important reference work reflecting the state-of-the-art in understanding and treating these challenging conditions.
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