Portal hypertension reversibility with treatment of underlying liver disease

Paul Y. Kwo, Marco A. Lacerdo

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Cirrhosis is the end-stage manifestation of chronic hepatitis with the most common causes of chronic hepatitis in developed countries being related to hepatitis B, hepatitis C, nonalcoholic fatty liver disease (NAFLD), and alcoholic liver disease. With more advanced cirrhosis, the development of portal hypertension occurs that leads to clinical decompensation. With improvement in therapies for hepatitis B and C, we have seen regression of fibrosis and even cirrhosis. However, there are limited data on reversal of portal hypertension. This review examines the direct and indirect evidence that we will be able to see regression of portal hypertension in those with cirrhosis.

Original languageEnglish (US)
Pages (from-to)219-224
Number of pages6
JournalCurrent Hepatitis Reports
Volume14
Issue number3
DOIs
StatePublished - Jul 22 2015

Keywords

  • Cirrhosis
  • Hepatitis B
  • Hepatitis C
  • Nonalcoholic steatohepatitis
  • Portal hypertension

ASJC Scopus subject areas

  • Hepatology
  • Virology

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