Portal vein thrombosis is a risk factor for poor early outcomes after liver transplantation

Analysis of risk factors and outcomes for portal vein thrombosis in waitlisted patients

Marwan Ghabril, Saurabh Agarwal, Marco Lacerda, Naga Chalasani, Paul Kwo, A. Joseph Tector

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Background. Portal vein thrombosis (PVT) is common in patients with cirrhosis, but the risk factors associated with PVT and its impact on outcomes following liver transplantation (LT) are not well defined. The objectives of this study were to determine the impact of PVT on post-LT patient and graft survival, waitlist outcomes, and the factors associated with PVT. Methods. A retrospective review of Organ Procurement and Transplant Network waitlist and LT data between 2002 and 2013 identified 48,570 patients undergoing their first LT, with 3321 (6.8%) reported to have PVT at LT. Results. Portal vein thrombosis was independently associated with increased 90-day mortality (odds ratio, 1.7; 95% confidence interval, 1.45-1.99; P

Original languageEnglish (US)
Pages (from-to)126-133
Number of pages8
JournalTransplantation
Volume100
Issue number1
DOIs
StatePublished - 2016

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Portal Vein
Liver Transplantation
Thrombosis
Tissue and Organ Procurement
Graft Survival
Fibrosis
Odds Ratio
Confidence Intervals
Transplants
Mortality

ASJC Scopus subject areas

  • Transplantation

Cite this

Portal vein thrombosis is a risk factor for poor early outcomes after liver transplantation : Analysis of risk factors and outcomes for portal vein thrombosis in waitlisted patients. / Ghabril, Marwan; Agarwal, Saurabh; Lacerda, Marco; Chalasani, Naga; Kwo, Paul; Joseph Tector, A.

In: Transplantation, Vol. 100, No. 1, 2016, p. 126-133.

Research output: Contribution to journalArticle

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AU - Lacerda, Marco

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AU - Kwo, Paul

AU - Joseph Tector, A.

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