Postoperative povidone-iodine prophylaxis in strabismus surgery

N. Marie Koederitz, Daniel E. Neely, David A. Plager, Blair Boehmer, Susan Ofner, Derek T. Sprunger, Naval Sondhi, Gavin Roberts

Research output: Contribution to journalArticle

15 Scopus citations


Purpose: While antibiotic/steroid combinations are routinely administered during the first week after strabismus surgery, they can be costly and inconvenient and may be unnecessary. This study compares the use of single-dose 5% povidone-iodine drops versus a week-long course of antibiotic/steroid as a prophylaxis against postoperative infection in extraocular muscle surgery. Methods: Retrospective chart review was performed of 1871 patients undergoing routine strabismus surgery. Patients received either a single application of 5% povidone-iodine solution to the operative eye(s) at the conclusion of the surgical procedure or a week-long course of topical antibiotic/steroid. Postoperative records were then reviewed to identify abnormalities or complications occurring during the first 2 months after surgery. Results: Complete documentation was found for 1603 patients. Single-dose povidone-iodine prophylaxis was used in 953 cases (59.5%), and a postoperative course of topical antibiotic/steroid combination was used in 650 cases (40.5%). Of the 1603 cases, possible infection occurred in 46 patients (2.87%). Of the 46 possible infections, 20 (3.08%) occurred in 650 patients on an antibiotic/steroid combination and 26 (2.83%) occurred in the 953 patients treated with single-dose povidone-iodine prophylaxis. This difference was not statistically significant (p = 0.6815). No cases of orbital cellulitis or endophthalmitis occurred in either group. Conclusions: Single-dose povidone-iodine is an inexpensive alternative to postoperative antibiotic/steroid prophylaxis following routine strabismus surgery performed through a fornix incision. Patients who had reoperations and limbal incisions were more likely to have complicated postoperative courses: antibiotic/steroid use in these groups may be beneficial.{A figure is presented}.

Original languageEnglish (US)
Pages (from-to)396-400
Number of pages5
JournalJournal of AAPOS
Issue number4
StatePublished - Aug 1 2008

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Ophthalmology

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    Koederitz, N. M., Neely, D. E., Plager, D. A., Boehmer, B., Ofner, S., Sprunger, D. T., Sondhi, N., & Roberts, G. (2008). Postoperative povidone-iodine prophylaxis in strabismus surgery. Journal of AAPOS, 12(4), 396-400.