Postpartum intracranial venous thrombosis associated with dysfunctional protein C and deficiency of protein S

Karen L. Roos, Robert M. Pascuzzi, Michael A. Kuharik, Amy D. Shapiro, Marilyn J. Manco-Johnson

Research output: Contribution to journalArticle

31 Scopus citations

Abstract

Development of intracranial dural sinus thrombosis in the postpartum period has been attributed to the hypercoagulable state of pregnancy. With increasing recognition of the role of the vitamin K-dependent proteins, protein C and protein S, in intracranial venous and arterial thrombotic events, our understanding of the cause of thrombotic events has improved. We report a patient who developed a superior sagittal sinus thrombosis in the second week postpartum, associated with a dysfunctional protein C and a decreased free protein S concentration.

Original languageEnglish (US)
Pages (from-to)492-494
Number of pages3
JournalObstetrics and gynecology
Volume76
Issue number3
StatePublished - Sep 1990

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Fingerprint Dive into the research topics of 'Postpartum intracranial venous thrombosis associated with dysfunctional protein C and deficiency of protein S'. Together they form a unique fingerprint.

  • Cite this