Potential of gallium-based leads for cardiac rhythm management devices

Aaron M. Kyle, Nichole Leahy-Glass, William Combs, Keith L. March

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We propose the use of gallium (Ga), a metal that is liquid at physiological temperatures, or one of its alloys, for use as the conducting material in the leads of implantable pacemakers or cardioverter defibrillators. It is proposed that a liquid conductor will make these leads more pliable and thus less susceptible to fracture in situ. As an initial step towards utilizing liquid gallium in leads, the biocompatibility of Ga was investigated via cytotoxicity, hemocompatibility, and intracutaneous injection testing. Unipolar pacing Ga prototypes were fabricated by adapting existing pacemaker leads. The electrical impedance and pulse transmission ability of these leads were examined. Ga was well tolerated both in vitro and in vivo. Additionally, the Ga prototypes conductors behaved as low magnitude resistances that did not distort pulses as generated by conventional pacemakers. These results indicate that Ga is an appropriate material for implantable cardiac stimulators and will be a focus of our liquid metal prototypes.

Original languageEnglish
Title of host publicationProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
Pages341-344
Number of pages4
DOIs
StatePublished - 2011
Event33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011 - Boston, MA, United States
Duration: Aug 30 2011Sep 3 2011

Other

Other33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011
CountryUnited States
CityBoston, MA
Period8/30/119/3/11

Fingerprint

Cardiac rhythm management
Gallium
Equipment and Supplies
Pacemakers
Liquids
Metals
Defibrillators
Acoustic impedance
Cytotoxicity
Electric Impedance
Liquid metals
Biocompatibility

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Signal Processing
  • Biomedical Engineering
  • Health Informatics

Cite this

Kyle, A. M., Leahy-Glass, N., Combs, W., & March, K. L. (2011). Potential of gallium-based leads for cardiac rhythm management devices. In Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS (pp. 341-344). [6090113] https://doi.org/10.1109/IEMBS.2011.6090113

Potential of gallium-based leads for cardiac rhythm management devices. / Kyle, Aaron M.; Leahy-Glass, Nichole; Combs, William; March, Keith L.

Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. 2011. p. 341-344 6090113.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Kyle, AM, Leahy-Glass, N, Combs, W & March, KL 2011, Potential of gallium-based leads for cardiac rhythm management devices. in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS., 6090113, pp. 341-344, 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011, Boston, MA, United States, 8/30/11. https://doi.org/10.1109/IEMBS.2011.6090113
Kyle AM, Leahy-Glass N, Combs W, March KL. Potential of gallium-based leads for cardiac rhythm management devices. In Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. 2011. p. 341-344. 6090113 https://doi.org/10.1109/IEMBS.2011.6090113
Kyle, Aaron M. ; Leahy-Glass, Nichole ; Combs, William ; March, Keith L. / Potential of gallium-based leads for cardiac rhythm management devices. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. 2011. pp. 341-344
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